Stable gene transfer of CCR5 and CXCR4 siRNAs by sleeping beauty transposon system to confer HIV-1 resistance
<p>Abstract</p> <p>Background</p> <p>Thus far gene therapy strategies for HIV/AIDS have used either conventional retroviral vectors or lentiviral vectors for gene transfer. Although highly efficient, their use poses a certain degree of risk in terms of viral mediated on...
Main Authors: | Akkina Ramesh, Tamhane Mayur |
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Format: | Article |
Language: | English |
Published: |
BMC
2008-07-01
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Series: | AIDS Research and Therapy |
Online Access: | http://www.aidsrestherapy.com/content/5/1/16 |
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