Research progress of erythropoietin in the treatment of diabetic retinopathy
Diabetic retinopathy(DR)is the most common complication of diabetes mellitus and remains the leading cause of blindness in working-age population. DR affects almost all the retinal cells, leading to the disruption and dysfunction of neurovascular unit and the neural-glial network. Erythropoietin(EPO...
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| Format: | Article |
| Language: | English |
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Press of International Journal of Ophthalmology (IJO PRESS)
2021-09-01
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| Series: | Guoji Yanke Zazhi |
| Subjects: | |
| Online Access: | http://ies.ijo.cn/cn_publish/2021/9/202109009.pdf |
| _version_ | 1818694090611490816 |
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| author | Dan-Dan Liu Guo-Tong Xu Jing-Fa Zhang |
| author_facet | Dan-Dan Liu Guo-Tong Xu Jing-Fa Zhang |
| author_sort | Dan-Dan Liu |
| collection | DOAJ |
| description | Diabetic retinopathy(DR)is the most common complication of diabetes mellitus and remains the leading cause of blindness in working-age population. DR affects almost all the retinal cells, leading to the disruption and dysfunction of neurovascular unit and the neural-glial network. Erythropoietin(EPO), a glycoprotein hormone, plays a pivotal role in neuroprotection, neurotrophy, anti-inflammation, anti-apoptosis and anti-oxidation etc., in various central nervous system diseases. This review discussed the protective effect of EPO in DR so as to provide new options for DR treatment. |
| first_indexed | 2024-12-17T13:24:03Z |
| format | Article |
| id | doaj.art-05f7acd33ad6453e93983355ae33cf58 |
| institution | Directory Open Access Journal |
| issn | 1672-5123 |
| language | English |
| last_indexed | 2024-12-17T13:24:03Z |
| publishDate | 2021-09-01 |
| publisher | Press of International Journal of Ophthalmology (IJO PRESS) |
| record_format | Article |
| series | Guoji Yanke Zazhi |
| spelling | doaj.art-05f7acd33ad6453e93983355ae33cf582022-12-21T21:46:46ZengPress of International Journal of Ophthalmology (IJO PRESS)Guoji Yanke Zazhi1672-51232021-09-012191539154210.3980/j.issn.1672-5123.2021.9.09202109009Research progress of erythropoietin in the treatment of diabetic retinopathyDan-Dan Liu0Guo-Tong Xu1Jing-Fa Zhang2Tongji University School of Medicine;Tongji Eye Institute, Shanghai 200092, ChinaTongji University School of Medicine;Tongji Eye Institute, Shanghai 200092, ChinaDepartment of Ophthalmology, Shanghai General Hospital;Shanghai First People's Hospital, Shanghai 200080, ChinaDiabetic retinopathy(DR)is the most common complication of diabetes mellitus and remains the leading cause of blindness in working-age population. DR affects almost all the retinal cells, leading to the disruption and dysfunction of neurovascular unit and the neural-glial network. Erythropoietin(EPO), a glycoprotein hormone, plays a pivotal role in neuroprotection, neurotrophy, anti-inflammation, anti-apoptosis and anti-oxidation etc., in various central nervous system diseases. This review discussed the protective effect of EPO in DR so as to provide new options for DR treatment.http://ies.ijo.cn/cn_publish/2021/9/202109009.pdfdiabetic retinopathyerythropoietinneurovascular unitneural-glial network |
| spellingShingle | Dan-Dan Liu Guo-Tong Xu Jing-Fa Zhang Research progress of erythropoietin in the treatment of diabetic retinopathy Guoji Yanke Zazhi diabetic retinopathy erythropoietin neurovascular unit neural-glial network |
| title | Research progress of erythropoietin in the treatment of diabetic retinopathy |
| title_full | Research progress of erythropoietin in the treatment of diabetic retinopathy |
| title_fullStr | Research progress of erythropoietin in the treatment of diabetic retinopathy |
| title_full_unstemmed | Research progress of erythropoietin in the treatment of diabetic retinopathy |
| title_short | Research progress of erythropoietin in the treatment of diabetic retinopathy |
| title_sort | research progress of erythropoietin in the treatment of diabetic retinopathy |
| topic | diabetic retinopathy erythropoietin neurovascular unit neural-glial network |
| url | http://ies.ijo.cn/cn_publish/2021/9/202109009.pdf |
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