Coupled mixed model for joint genetic analysis of complex disorders with two independently collected data sets

Coupled mixed model for joint genetic analysis of complex disorders with two independently collected data sets

Abstract Background In the last decade, Genome-wide Association studies (GWASs) have contributed to decoding the human genome by uncovering many genetic variations associated with various diseases. Many follow-up investigations involve joint analysis of multiple independently generated GWAS data set...

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Bibliographic Details
Main Authors: Haohan Wang, Fen Pei, Michael M. Vanyukov, Ivet Bahar, Wei Wu, Eric P. Xing
Format: Article
Language:English
Published: BMC 2021-02-01
Series:BMC Bioinformatics
Subjects:
Joint analysis
Mixed model
Deconfounding
Online Access:https://doi.org/10.1186/s12859-021-03959-2

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