Mind the brain gap: The worldwide distribution of neuroimaging research on adolescent depression
Adolescents comprise one fourth of the world's population, with about 90% of them living in low- and middle-income countries (LMICs). The incidence of depression markedly increases during adolescence, making the disorder a leading cause of disease-related disability in this age group. However,...
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Elsevier
2021-05-01
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Series: | NeuroImage |
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Online Access: | http://www.sciencedirect.com/science/article/pii/S1053811921001427 |
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author | Lucas Battel Fernanda Cunegatto Anna Viduani Helen L. Fisher Brandon A. Kohrt Valeria Mondelli Johnna R. Swartz Christian Kieling |
author_facet | Lucas Battel Fernanda Cunegatto Anna Viduani Helen L. Fisher Brandon A. Kohrt Valeria Mondelli Johnna R. Swartz Christian Kieling |
author_sort | Lucas Battel |
collection | DOAJ |
description | Adolescents comprise one fourth of the world's population, with about 90% of them living in low- and middle-income countries (LMICs). The incidence of depression markedly increases during adolescence, making the disorder a leading cause of disease-related disability in this age group. However, most research on adolescent depression has been performed in high-income countries (HICs). To ascertain the extent to which this disparity operates in neuroimaging research, a systematic review of the literature was performed. A total of 148 studies were identified, with neuroimaging data available for 4,729 adolescents with depression. When stratified by income group, 122 (82%) studies originated from HICs, while 26 (18%) were conducted in LMICs, for a total of 3,705 and 1,024 adolescents with depression respectively. A positive Spearman rank correlation was observed between country per capita income and sample size (rs=0.673, p = 0.023). Our results support the previous reports showing a large disparity between the number of studies and the adolescent population per world region. Future research comparing neuroimaging findings across populations from HICs and LMICs may provide unique insights to enhance our understanding of the neurobiological processes underlying the development of depression. |
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format | Article |
id | doaj.art-05f9019d816b481192e161caf37075b2 |
institution | Directory Open Access Journal |
issn | 1095-9572 |
language | English |
last_indexed | 2024-12-16T11:01:54Z |
publishDate | 2021-05-01 |
publisher | Elsevier |
record_format | Article |
series | NeuroImage |
spelling | doaj.art-05f9019d816b481192e161caf37075b22022-12-21T22:33:59ZengElsevierNeuroImage1095-95722021-05-01231117865Mind the brain gap: The worldwide distribution of neuroimaging research on adolescent depressionLucas Battel0Fernanda Cunegatto1Anna Viduani2Helen L. Fisher3Brandon A. Kohrt4Valeria Mondelli5Johnna R. Swartz6Christian Kieling7Department of Psychiatry, Universidade Federal do Rio Grande do Sul (UFRGS), Child & Adolescent Psychiatry Division, Hospital de Clínicas de Porto Alegre (HCPA), Rua Ramiro Barcelos, 2350 – 400N, Porto Alegre, RS 90035003, BrazilDepartment of Psychiatry, Universidade Federal do Rio Grande do Sul (UFRGS), Child & Adolescent Psychiatry Division, Hospital de Clínicas de Porto Alegre (HCPA), Rua Ramiro Barcelos, 2350 – 400N, Porto Alegre, RS 90035003, BrazilDepartment of Psychiatry, Universidade Federal do Rio Grande do Sul (UFRGS), Child & Adolescent Psychiatry Division, Hospital de Clínicas de Porto Alegre (HCPA), Rua Ramiro Barcelos, 2350 – 400N, Porto Alegre, RS 90035003, BrazilKing's College London, Social, Genetic & Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, 16 De Crespigny Park, London SE5 8AF, United Kingdom; ESRC Centre for Society and Mental Health, Virginia Woolf Building, 22 Kingsway, London WC2B 6NR, United KingdomDivision of Global Mental Health, Department of Psychiatry, School of Medicine and Health Sciences, The George Washington University, 2120L St NW, Ste 600, Washington DC 20037, United StatesKing's College London, Department of Psychological Medicine, Institute of Psychiatry, Psychology & Neuroscience, Cutcombe Road, London SE5 9RT, United Kingdom; National Institute for Health Research Mental Health Biomedical Research Centre, South London and Maudsley NHS Foundation Trust and King's College London, London, United KingdomDepartment of Human Ecology, University of California, Davis, One Shields Ave, Davis, CA 95616, United StatesDepartment of Psychiatry, UFRGS, Child & Adolescent Psychiatry Division, HCPA, Rua Ramiro Barcelos, 2350 – 400N, Porto Alegre, RS 90035003, Brazil; Corresponding author.Adolescents comprise one fourth of the world's population, with about 90% of them living in low- and middle-income countries (LMICs). The incidence of depression markedly increases during adolescence, making the disorder a leading cause of disease-related disability in this age group. However, most research on adolescent depression has been performed in high-income countries (HICs). To ascertain the extent to which this disparity operates in neuroimaging research, a systematic review of the literature was performed. A total of 148 studies were identified, with neuroimaging data available for 4,729 adolescents with depression. When stratified by income group, 122 (82%) studies originated from HICs, while 26 (18%) were conducted in LMICs, for a total of 3,705 and 1,024 adolescents with depression respectively. A positive Spearman rank correlation was observed between country per capita income and sample size (rs=0.673, p = 0.023). Our results support the previous reports showing a large disparity between the number of studies and the adolescent population per world region. Future research comparing neuroimaging findings across populations from HICs and LMICs may provide unique insights to enhance our understanding of the neurobiological processes underlying the development of depression.http://www.sciencedirect.com/science/article/pii/S1053811921001427AdolescenceDepressionNeuroimagingIncomeInequalityDeveloping countries |
spellingShingle | Lucas Battel Fernanda Cunegatto Anna Viduani Helen L. Fisher Brandon A. Kohrt Valeria Mondelli Johnna R. Swartz Christian Kieling Mind the brain gap: The worldwide distribution of neuroimaging research on adolescent depression NeuroImage Adolescence Depression Neuroimaging Income Inequality Developing countries |
title | Mind the brain gap: The worldwide distribution of neuroimaging research on adolescent depression |
title_full | Mind the brain gap: The worldwide distribution of neuroimaging research on adolescent depression |
title_fullStr | Mind the brain gap: The worldwide distribution of neuroimaging research on adolescent depression |
title_full_unstemmed | Mind the brain gap: The worldwide distribution of neuroimaging research on adolescent depression |
title_short | Mind the brain gap: The worldwide distribution of neuroimaging research on adolescent depression |
title_sort | mind the brain gap the worldwide distribution of neuroimaging research on adolescent depression |
topic | Adolescence Depression Neuroimaging Income Inequality Developing countries |
url | http://www.sciencedirect.com/science/article/pii/S1053811921001427 |
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