Dissecting lung development and fibrosis at single-cell resolution

Editorial summary Single-cell transcriptome profiling has enabled high-resolution analysis of cellular populations in tissues during development, health, and disease. Recent studies make innovative use of single-cell RNA sequencing (scRNAseq) to investigate mechanisms that allow immune cells to inte...

Full description

Bibliographic Details
Main Authors: Donna L. Farber, Peter A. Sims
Format: Article
Language:English
Published: BMC 2019-05-01
Series:Genome Medicine
Online Access:http://link.springer.com/article/10.1186/s13073-019-0645-7
_version_ 1818173820854337536
author Donna L. Farber
Peter A. Sims
author_facet Donna L. Farber
Peter A. Sims
author_sort Donna L. Farber
collection DOAJ
description Editorial summary Single-cell transcriptome profiling has enabled high-resolution analysis of cellular populations in tissues during development, health, and disease. Recent studies make innovative use of single-cell RNA sequencing (scRNAseq) to investigate mechanisms that allow immune cells to interact with tissue components in the lung during development and fibrotic lung disease.
first_indexed 2024-12-11T19:34:35Z
format Article
id doaj.art-05f96fe26db84761b7633f52a90de39d
institution Directory Open Access Journal
issn 1756-994X
language English
last_indexed 2024-12-11T19:34:35Z
publishDate 2019-05-01
publisher BMC
record_format Article
series Genome Medicine
spelling doaj.art-05f96fe26db84761b7633f52a90de39d2022-12-22T00:53:11ZengBMCGenome Medicine1756-994X2019-05-011111310.1186/s13073-019-0645-7Dissecting lung development and fibrosis at single-cell resolutionDonna L. Farber0Peter A. Sims1Columbia Center for Translational Immunology, Columbia University Irving Medical CenterDepartment of Systems Biology, Columbia University Irving Medical CenterEditorial summary Single-cell transcriptome profiling has enabled high-resolution analysis of cellular populations in tissues during development, health, and disease. Recent studies make innovative use of single-cell RNA sequencing (scRNAseq) to investigate mechanisms that allow immune cells to interact with tissue components in the lung during development and fibrotic lung disease.http://link.springer.com/article/10.1186/s13073-019-0645-7
spellingShingle Donna L. Farber
Peter A. Sims
Dissecting lung development and fibrosis at single-cell resolution
Genome Medicine
title Dissecting lung development and fibrosis at single-cell resolution
title_full Dissecting lung development and fibrosis at single-cell resolution
title_fullStr Dissecting lung development and fibrosis at single-cell resolution
title_full_unstemmed Dissecting lung development and fibrosis at single-cell resolution
title_short Dissecting lung development and fibrosis at single-cell resolution
title_sort dissecting lung development and fibrosis at single cell resolution
url http://link.springer.com/article/10.1186/s13073-019-0645-7
work_keys_str_mv AT donnalfarber dissectinglungdevelopmentandfibrosisatsinglecellresolution
AT peterasims dissectinglungdevelopmentandfibrosisatsinglecellresolution