Dissecting lung development and fibrosis at single-cell resolution
Editorial summary Single-cell transcriptome profiling has enabled high-resolution analysis of cellular populations in tissues during development, health, and disease. Recent studies make innovative use of single-cell RNA sequencing (scRNAseq) to investigate mechanisms that allow immune cells to inte...
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Format: | Article |
Language: | English |
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BMC
2019-05-01
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Series: | Genome Medicine |
Online Access: | http://link.springer.com/article/10.1186/s13073-019-0645-7 |
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author | Donna L. Farber Peter A. Sims |
author_facet | Donna L. Farber Peter A. Sims |
author_sort | Donna L. Farber |
collection | DOAJ |
description | Editorial summary Single-cell transcriptome profiling has enabled high-resolution analysis of cellular populations in tissues during development, health, and disease. Recent studies make innovative use of single-cell RNA sequencing (scRNAseq) to investigate mechanisms that allow immune cells to interact with tissue components in the lung during development and fibrotic lung disease. |
first_indexed | 2024-12-11T19:34:35Z |
format | Article |
id | doaj.art-05f96fe26db84761b7633f52a90de39d |
institution | Directory Open Access Journal |
issn | 1756-994X |
language | English |
last_indexed | 2024-12-11T19:34:35Z |
publishDate | 2019-05-01 |
publisher | BMC |
record_format | Article |
series | Genome Medicine |
spelling | doaj.art-05f96fe26db84761b7633f52a90de39d2022-12-22T00:53:11ZengBMCGenome Medicine1756-994X2019-05-011111310.1186/s13073-019-0645-7Dissecting lung development and fibrosis at single-cell resolutionDonna L. Farber0Peter A. Sims1Columbia Center for Translational Immunology, Columbia University Irving Medical CenterDepartment of Systems Biology, Columbia University Irving Medical CenterEditorial summary Single-cell transcriptome profiling has enabled high-resolution analysis of cellular populations in tissues during development, health, and disease. Recent studies make innovative use of single-cell RNA sequencing (scRNAseq) to investigate mechanisms that allow immune cells to interact with tissue components in the lung during development and fibrotic lung disease.http://link.springer.com/article/10.1186/s13073-019-0645-7 |
spellingShingle | Donna L. Farber Peter A. Sims Dissecting lung development and fibrosis at single-cell resolution Genome Medicine |
title | Dissecting lung development and fibrosis at single-cell resolution |
title_full | Dissecting lung development and fibrosis at single-cell resolution |
title_fullStr | Dissecting lung development and fibrosis at single-cell resolution |
title_full_unstemmed | Dissecting lung development and fibrosis at single-cell resolution |
title_short | Dissecting lung development and fibrosis at single-cell resolution |
title_sort | dissecting lung development and fibrosis at single cell resolution |
url | http://link.springer.com/article/10.1186/s13073-019-0645-7 |
work_keys_str_mv | AT donnalfarber dissectinglungdevelopmentandfibrosisatsinglecellresolution AT peterasims dissectinglungdevelopmentandfibrosisatsinglecellresolution |