Development and Validation of Pomalidomide Determination in Human Plasma by HPLC-MS/MS Method

Development and Validation of Pomalidomide Determination in Human Plasma by HPLC-MS/MS Method

Introduction. B-cell malignancies of the plasma cell leads to the second most spread hematological malignancy disease, called multiple myeloma. Pomalidomide is used in case of previous multiple myeloma ineffective treatment. Pomalidomide is a thalidomide synthetic derived, approved as immunomodulato...

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Main Authors: T. N. Komarov, I. E. Shohin, M. A. Tokareva, O. A. Archakova, D. S. Bogdanova, A. A. Aleshina, N. S. Bagaeva, V. V. Davydanova, N. P. Sadchikova
Format: Article
Language:Russian
Published: LLC Center of Pharmaceutical Analytics (LLC «CPHA») 2020-11-01
Series:Разработка и регистрация лекарственных средств
Subjects:
pomalidomide
plasma
hplc-ms/ms
validation
bioequivalence
Online Access:https://www.pharmjournal.ru/jour/article/view/864

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