Intracellular metabolic adaptation of intraepithelial CD4+CD8αα+ T lymphocytes

Intracellular metabolic adaptation of intraepithelial CD4+CD8αα+ T lymphocytes

Summary: Intestinal intraepithelial lymphocytes (IELs), the first line of defense against microbial and dietary antigens, are classified as natural or induced based on their origin and receptor expression. Induced CD4+CD8αα+TCRβ+ T cells (double positive, DPIELs) originated from CD4+CD8α−TCRβ+ T cel...

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Bibliographic Details
Main Authors: Yosuke Harada, Tomohisa Sujino, Kentaro Miyamoto, Ena Nomura, Yusuke Yoshimatsu, Shun Tanemoto, Satoko Umeda, Keiko Ono, Yohei Mikami, Nobuhiro Nakamoto, Kaoru Takabayashi, Naoki Hosoe, Haruhiko Ogata, Tuneo Ikenoue, Atsushi Hirao, Yoshiaki Kubota, Takanori Kanai
Format: Article
Language:English
Published: Elsevier 2022-04-01
Series:iScience
Subjects:
Biological sciences
Immunology
Components of the immune system
Cell biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222002917

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