Clinical characteristics of Chilean patients with rheumatic diseases and COVID-19: data from the Covid-19 Global Rheumatology Alliance physician-reported registry
Objective: The coronavirus disease 2019 (COVID-19) pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2), has registered more than 234 million confirmed cases and more than 4.7 million deaths throughout the world until October 2, 2021. During the last few months, a sig...
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| Format: | Article |
| Language: | English |
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Panamerican League of Associations of Rheumatology (PANLAR)
2022-04-01
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| Series: | Global Rheumatology |
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| Online Access: | https://www.globalrheumpanlar.org/manuscrito-comentarios-y-respuestas/brief-report-caracteristicas-clinicas-de-pacientes-chilenos-con?language=en |
| _version_ | 1811280271268380672 |
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| author | Oriela Martínez Hernández Francisca Valenzuela Sebastian Ibañez |
| author_facet | Oriela Martínez Hernández Francisca Valenzuela Sebastian Ibañez |
| author_sort | Oriela Martínez Hernández |
| collection | DOAJ |
| description | Objective: The coronavirus disease 2019 (COVID-19) pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2), has registered more than 234 million confirmed cases and more than 4.7 million deaths throughout the world until October 2, 2021. During the last few months, a significant number of reports of COVID-19 in patients with rheumatic diseases have been published. In this study the objective is to report the clinical characteristics of Chilean patients with rheumatic diseases and COVID-19 reported in the “Global Rheumatology Alliance” (GRA) physician registration platform.
Materials and Methods: Chilean patients with rheumatic diseases and COVID-19 were included in the Covid-19 GRA physician-reported registry.
Results: 54 patients were included. The most common primary rheumatic disease was rheumatoid arthritis (RA) with 28 cases (51.9%). 30 patients (55.6%) used corticosteroids, of which 20 (66.7%) used a dose of 10 mg or less. 33 patients (61.1%) only used conventional DMARDs, 4 (7.4%) only biological, and 6 (11.1%) the combination. A total of 35 patients (64.8%) had to be hospitalized. 2 patients (3.7%) died. 26 patients of the 35 hospitalized (74.2%) required some type of ventilatory support, of which 5 (19.2%) required non-invasive and 8 (30.8%) invasive mechanical ventilation or extracorporeal membrane oxygenation (ECMO).
Discussion: Most of included Chilean rheumatic patients were hospitalized, with a low mortality rate but with a high percentage of patients requiring at least non-invasive mechanical ventilation. |
| first_indexed | 2024-04-13T01:11:46Z |
| format | Article |
| id | doaj.art-060448d918f845a1b6eabd2e06a7d3ff |
| institution | Directory Open Access Journal |
| issn | 2709-5533 |
| language | English |
| last_indexed | 2024-04-13T01:11:46Z |
| publishDate | 2022-04-01 |
| publisher | Panamerican League of Associations of Rheumatology (PANLAR) |
| record_format | Article |
| series | Global Rheumatology |
| spelling | doaj.art-060448d918f845a1b6eabd2e06a7d3ff2022-12-22T03:09:08ZengPanamerican League of Associations of Rheumatology (PANLAR)Global Rheumatology2709-55332022-04-01410.46856/grp.12.e113Clinical characteristics of Chilean patients with rheumatic diseases and COVID-19: data from the Covid-19 Global Rheumatology Alliance physician-reported registryOriela Martínez Hernández0https://orcid.org/0000-0002-5102-2301Francisca Valenzuela1Sebastian Ibañez2https://orcid.org/0000-0002-9577-3078Hospital Padre HurtadoHospital Padre HurtadoHospital Padre HurtadoObjective: The coronavirus disease 2019 (COVID-19) pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2), has registered more than 234 million confirmed cases and more than 4.7 million deaths throughout the world until October 2, 2021. During the last few months, a significant number of reports of COVID-19 in patients with rheumatic diseases have been published. In this study the objective is to report the clinical characteristics of Chilean patients with rheumatic diseases and COVID-19 reported in the “Global Rheumatology Alliance” (GRA) physician registration platform. Materials and Methods: Chilean patients with rheumatic diseases and COVID-19 were included in the Covid-19 GRA physician-reported registry. Results: 54 patients were included. The most common primary rheumatic disease was rheumatoid arthritis (RA) with 28 cases (51.9%). 30 patients (55.6%) used corticosteroids, of which 20 (66.7%) used a dose of 10 mg or less. 33 patients (61.1%) only used conventional DMARDs, 4 (7.4%) only biological, and 6 (11.1%) the combination. A total of 35 patients (64.8%) had to be hospitalized. 2 patients (3.7%) died. 26 patients of the 35 hospitalized (74.2%) required some type of ventilatory support, of which 5 (19.2%) required non-invasive and 8 (30.8%) invasive mechanical ventilation or extracorporeal membrane oxygenation (ECMO). Discussion: Most of included Chilean rheumatic patients were hospitalized, with a low mortality rate but with a high percentage of patients requiring at least non-invasive mechanical ventilation.https://www.globalrheumpanlar.org/manuscrito-comentarios-y-respuestas/brief-report-caracteristicas-clinicas-de-pacientes-chilenos-con?language=enrheumatic diseasepandemiccovid-19brief report |
| spellingShingle | Oriela Martínez Hernández Francisca Valenzuela Sebastian Ibañez Clinical characteristics of Chilean patients with rheumatic diseases and COVID-19: data from the Covid-19 Global Rheumatology Alliance physician-reported registry Global Rheumatology rheumatic disease pandemic covid-19 brief report |
| title | Clinical characteristics of Chilean patients with rheumatic diseases and COVID-19: data from the Covid-19 Global Rheumatology Alliance physician-reported registry |
| title_full | Clinical characteristics of Chilean patients with rheumatic diseases and COVID-19: data from the Covid-19 Global Rheumatology Alliance physician-reported registry |
| title_fullStr | Clinical characteristics of Chilean patients with rheumatic diseases and COVID-19: data from the Covid-19 Global Rheumatology Alliance physician-reported registry |
| title_full_unstemmed | Clinical characteristics of Chilean patients with rheumatic diseases and COVID-19: data from the Covid-19 Global Rheumatology Alliance physician-reported registry |
| title_short | Clinical characteristics of Chilean patients with rheumatic diseases and COVID-19: data from the Covid-19 Global Rheumatology Alliance physician-reported registry |
| title_sort | clinical characteristics of chilean patients with rheumatic diseases and covid 19 data from the covid 19 global rheumatology alliance physician reported registry |
| topic | rheumatic disease pandemic covid-19 brief report |
| url | https://www.globalrheumpanlar.org/manuscrito-comentarios-y-respuestas/brief-report-caracteristicas-clinicas-de-pacientes-chilenos-con?language=en |
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