Circulating tumour DNA is a promising biomarker for risk stratification of central chondrosarcoma with IDH1/2 and GNAS mutations

Circulating tumour DNA is a promising biomarker for risk stratification of central chondrosarcoma with IDH1/2 and GNAS mutations

Chondrosarcoma (CS) is a rare tumour type and the most common primary malignant bone cancer in adults. The prognosis, currently based on tumour grade, imaging and anatomical location, is not reliable, and more objective biomarkers are required. We aimed to determine whether the level of circulating...

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Bibliografiska uppgifter
Huvudupphovsmän: Iben Lyskjær, Christopher Davies, Anna‐Christina Strobl, Joanna Hindley, Steven James, Radhesh K. Lalam, William Cross, Geoff Hide, Kenneth S. Rankin, Lee Jeys, Roberto Tirabosco, Jonathan Stevenson, Genomics England Research Consortium, Paul O’Donnell, Paul Cool, Adrienne M. Flanagan
Materialtyp: Artikel
Språk:English
Publicerad: Wiley 2021-12-01
Serie:Molecular Oncology
Ämnen:
chondrosarcoma
circulating tumour DNA
GNAS
IDH1
IDH2
prognosis
Länkar:https://doi.org/10.1002/1878-0261.13102

Internet

https://doi.org/10.1002/1878-0261.13102

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