A caveolin-1 dependent glucose-6-phosphatase trafficking contributes to hepatic glucose production

A caveolin-1 dependent glucose-6-phosphatase trafficking contributes to hepatic glucose production

Objective: Deregulation of hepatic glucose production is a key driver in the pathogenesis of diabetes, but its short-term regulation is incompletely deciphered. According to textbooks, glucose is produced in the endoplasmic reticulum by glucose-6-phosphatase (G6Pase) and then exported in the blood b...

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Bibliographic Details
Main Authors: Amandine Gautier-Stein, Julien Chilloux, Maud Soty, Bernard Thorens, Christophe Place, Carine Zitoun, Adeline Duchampt, Lorine Da Costa, Fabienne Rajas, Christophe Lamaze, Gilles Mithieux
Format: Article
Language:English
Published: Elsevier 2023-04-01
Series:Molecular Metabolism
Subjects:
Liver
Glucose-6 phosphatase
Gluconeogenesis
Intracellular glucose transport
Caveolin 1
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877823000340

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