Comparison Of Less Invasive Surfactant Delivery Techniques In Respiratory Distress Syndrome
Background: This study was conducted to evaluate and compare the effectiveness of newly developed minimal invasive methods for surfactant administration (LISA by using Magill forceps, INSURE) Methods: The research was conducted on 15 patients between 685-2100 gr weight, requiring surfactant administ...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Rabia Yılmaz
2020-12-01
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| Series: | Journal of Contemporary Medicine |
| Subjects: | |
| Online Access: | https://dergipark.org.tr/tr/download/article-file/1032413 |
| _version_ | 1827980171490099200 |
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| author | Erdal Taşkın Yasemin Çoban |
| author_facet | Erdal Taşkın Yasemin Çoban |
| author_sort | Erdal Taşkın |
| collection | DOAJ |
| description | Background: This study was conducted to evaluate and compare the effectiveness of newly developed minimal invasive methods for surfactant administration (LISA by using Magill forceps, INSURE)
Methods: The research was conducted on 15 patients between 685-2100 gr weight, requiring surfactant administration. Poractant alpha, dose 200 mg/kg, was administered to patients with spontaneous breathing on continuous positive airway pressure support. LISA was used to administer surfactant to 7 of 15 patients, whereas 8 of them had surfactant administered using the INSURE method.
Results: The data regarding the delivery method, birth weight, gender, prenatal history, usage of steroids, APGAR scores and other data about the patients until hospital discharge were recorded. Desaturation and bradycardia for 3-4 minutes were observed in 71% (5/7) of LISA and 87.5% (7/8) of INSURE cases. Bradycardia was observed in 4 of 8 patients from the INSURE group and positive ventilation was needed. From the INSURE group, 3 patients died; one of 15 had ROP and this patient was from the INSURE group. No difference was found among the groups regarding required duration of O2 and days of hospital stay (p lt;0.05). The thin catheter group had significantly fewer median days on mechanical ventilation and lower rate of mortality (p lt;0.05).
Conclusions: When there is no need for mechanical ventilation, intubation for surfactant administration was determined not to be necessary in the present study. LISA was observed to be the best method for surfactant administration among the methods without intubation. |
| first_indexed | 2024-04-09T21:49:27Z |
| format | Article |
| id | doaj.art-060be7f639df4e9fade675103f1c8056 |
| institution | Directory Open Access Journal |
| issn | 2667-7180 |
| language | English |
| last_indexed | 2024-04-09T21:49:27Z |
| publishDate | 2020-12-01 |
| publisher | Rabia Yılmaz |
| record_format | Article |
| series | Journal of Contemporary Medicine |
| spelling | doaj.art-060be7f639df4e9fade675103f1c80562023-03-24T19:43:24ZengRabia YılmazJournal of Contemporary Medicine2667-71802020-12-0110449349810.16899/jcm.7129311809Comparison Of Less Invasive Surfactant Delivery Techniques In Respiratory Distress SyndromeErdal Taşkın0Yasemin Çoban1FIRAT ÜNİVERSİTESİ, TIP FAKÜLTESİHATAY DEVLET HASTANESİBackground: This study was conducted to evaluate and compare the effectiveness of newly developed minimal invasive methods for surfactant administration (LISA by using Magill forceps, INSURE) Methods: The research was conducted on 15 patients between 685-2100 gr weight, requiring surfactant administration. Poractant alpha, dose 200 mg/kg, was administered to patients with spontaneous breathing on continuous positive airway pressure support. LISA was used to administer surfactant to 7 of 15 patients, whereas 8 of them had surfactant administered using the INSURE method. Results: The data regarding the delivery method, birth weight, gender, prenatal history, usage of steroids, APGAR scores and other data about the patients until hospital discharge were recorded. Desaturation and bradycardia for 3-4 minutes were observed in 71% (5/7) of LISA and 87.5% (7/8) of INSURE cases. Bradycardia was observed in 4 of 8 patients from the INSURE group and positive ventilation was needed. From the INSURE group, 3 patients died; one of 15 had ROP and this patient was from the INSURE group. No difference was found among the groups regarding required duration of O2 and days of hospital stay (p lt;0.05). The thin catheter group had significantly fewer median days on mechanical ventilation and lower rate of mortality (p lt;0.05). Conclusions: When there is no need for mechanical ventilation, intubation for surfactant administration was determined not to be necessary in the present study. LISA was observed to be the best method for surfactant administration among the methods without intubation.https://dergipark.org.tr/tr/download/article-file/1032413respiratuar distres sendromusurfaktankomplikasyonveriliş yöntemicpaprespiratory distress syndromesurfactantcomplicationsnew method |
| spellingShingle | Erdal Taşkın Yasemin Çoban Comparison Of Less Invasive Surfactant Delivery Techniques In Respiratory Distress Syndrome Journal of Contemporary Medicine respiratuar distres sendromu surfaktan komplikasyon veriliş yöntemi cpap respiratory distress syndrome surfactant complications new method |
| title | Comparison Of Less Invasive Surfactant Delivery Techniques In Respiratory Distress Syndrome |
| title_full | Comparison Of Less Invasive Surfactant Delivery Techniques In Respiratory Distress Syndrome |
| title_fullStr | Comparison Of Less Invasive Surfactant Delivery Techniques In Respiratory Distress Syndrome |
| title_full_unstemmed | Comparison Of Less Invasive Surfactant Delivery Techniques In Respiratory Distress Syndrome |
| title_short | Comparison Of Less Invasive Surfactant Delivery Techniques In Respiratory Distress Syndrome |
| title_sort | comparison of less invasive surfactant delivery techniques in respiratory distress syndrome |
| topic | respiratuar distres sendromu surfaktan komplikasyon veriliş yöntemi cpap respiratory distress syndrome surfactant complications new method |
| url | https://dergipark.org.tr/tr/download/article-file/1032413 |
| work_keys_str_mv | AT erdaltaskın comparisonoflessinvasivesurfactantdeliverytechniquesinrespiratorydistresssyndrome AT yasemincoban comparisonoflessinvasivesurfactantdeliverytechniquesinrespiratorydistresssyndrome |