Treatment of acute pancreatitis

There is no specific treatment for acute pancreatitis. Majority of patients with acute pancreatitis respond to medical therapy. Supportive measures and close observations represent the cornerstone of the medical therapy. Failure to respond to medical treatment may indicate choledocholithiasis or inf...

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Main Author: Al-Mofleh Ibrahim
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 1998-01-01
Series:The Saudi Journal of Gastroenterology
Online Access:http://www.saudijgastro.com/article.asp?issn=1319-3767;year=1998;volume=4;issue=1;spage=1;epage=7;aulast=Al-Mofleh
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author Al-Mofleh Ibrahim
author_facet Al-Mofleh Ibrahim
author_sort Al-Mofleh Ibrahim
collection DOAJ
description There is no specific treatment for acute pancreatitis. Majority of patients with acute pancreatitis respond to medical therapy. Supportive measures and close observations represent the cornerstone of the medical therapy. Failure to respond to medical treatment may indicate choledocholithiasis or infected necrosis. Endoscopic papillotomy with stone retrieval is beneficial in patients with severe biliary pancreatitis. Image-guided fine needle aspiration and bacteriological examination of aspirate is reliable in detecting infection and deliniating causative pathogen. Surgical debridement is the method of choice for treatment of infected necrosis. In contrast, in pancreatic abscess, surgery is preserved for those, who do not respond to percutaneous drainage combined with antibiotics. The benefit of antisecretory and antiproteolytic agents is debatable. A combination of antioxidants, calcium channel antagonists and antibiotics may play a major role in the treatment of acute pancreatitis in the future.
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spelling doaj.art-060d1bfa0f94470d9108864210e358e52022-12-22T01:25:05ZengWolters Kluwer Medknow PublicationsThe Saudi Journal of Gastroenterology1319-37671998-01-014117Treatment of acute pancreatitisAl-Mofleh IbrahimThere is no specific treatment for acute pancreatitis. Majority of patients with acute pancreatitis respond to medical therapy. Supportive measures and close observations represent the cornerstone of the medical therapy. Failure to respond to medical treatment may indicate choledocholithiasis or infected necrosis. Endoscopic papillotomy with stone retrieval is beneficial in patients with severe biliary pancreatitis. Image-guided fine needle aspiration and bacteriological examination of aspirate is reliable in detecting infection and deliniating causative pathogen. Surgical debridement is the method of choice for treatment of infected necrosis. In contrast, in pancreatic abscess, surgery is preserved for those, who do not respond to percutaneous drainage combined with antibiotics. The benefit of antisecretory and antiproteolytic agents is debatable. A combination of antioxidants, calcium channel antagonists and antibiotics may play a major role in the treatment of acute pancreatitis in the future.http://www.saudijgastro.com/article.asp?issn=1319-3767;year=1998;volume=4;issue=1;spage=1;epage=7;aulast=Al-Mofleh
spellingShingle Al-Mofleh Ibrahim
Treatment of acute pancreatitis
The Saudi Journal of Gastroenterology
title Treatment of acute pancreatitis
title_full Treatment of acute pancreatitis
title_fullStr Treatment of acute pancreatitis
title_full_unstemmed Treatment of acute pancreatitis
title_short Treatment of acute pancreatitis
title_sort treatment of acute pancreatitis
url http://www.saudijgastro.com/article.asp?issn=1319-3767;year=1998;volume=4;issue=1;spage=1;epage=7;aulast=Al-Mofleh
work_keys_str_mv AT almoflehibrahim treatmentofacutepancreatitis