Genetic diversity in Borrelia burgdorferi sensu lato
Background: Borrelia burgdorferi sensu lato complex comprise a number of Borrelia species related to Lyme Borreliosis (LB). Three of the human pathogenic species, Borrelia burgdorferi sensu stricto, Borrelia afzelii and Borrelia garinii are common in Europe. Human LB infection is a complex disease a...
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| Format: | Article |
| Language: | Danish |
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NITO - Bioingeniørfaglig institutt
2014-12-01
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| Series: | Bioingeniøren |
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| Online Access: | https://bioingenioren.no/fag/fag-oversiktsartikkel/genetisk-mangfold-i-borrelia-burgdorferi-sensu-lato/ |
| _version_ | 1818232444873080832 |
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| author | Ann-Kristin Tveten |
| author_facet | Ann-Kristin Tveten |
| author_sort | Ann-Kristin Tveten |
| collection | DOAJ |
| description | Background: Borrelia burgdorferi sensu lato complex comprise a number of Borrelia species related to Lyme Borreliosis (LB). Three of the human pathogenic species, Borrelia burgdorferi sensu stricto, Borrelia afzelii and Borrelia garinii are common in Europe. Human LB infection is a complex disease and the different Borrelia species display different clinical manifestations.
Materials and methods: The study is based on search in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/) and global MLST databases (http://www.mlst.net/ and http://pubmlst.org/). Search keywords; “MLST, Borrelia, Genetics, Taxonomy, Host, Evolution, Lyme”. The majority of authors of the articles used are working in the major research groups that study Borrelia-MLST worldwide.
Discussion: Borrelia taxonomy is in continual development and multilocus sequence typing (MLST) is one of the methods used for genetic characterization of Borrelia species. MLST is an analysis tool that provides results comparable worldwide through an online database (borrelia.mlst.net). The method is based on a set of strict criteria, which have to be met in order for the MLST to be applied in taxonomy and evolutionary studies. MLST has demonstrated a great diversity among Borrelia strains. Research indicates that the diversity among Borrelia strains can be related to determinants such as host and geographic origin.
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| first_indexed | 2024-12-12T11:06:23Z |
| format | Article |
| id | doaj.art-060f332b4e4347b68f7efb1c9465fb4c |
| institution | Directory Open Access Journal |
| issn | 0801-6828 1890-1875 |
| language | Danish |
| last_indexed | 2024-12-12T11:06:23Z |
| publishDate | 2014-12-01 |
| publisher | NITO - Bioingeniørfaglig institutt |
| record_format | Article |
| series | Bioingeniøren |
| spelling | doaj.art-060f332b4e4347b68f7efb1c9465fb4c2022-12-22T00:26:23ZdanNITO - Bioingeniørfaglig instituttBioingeniøren0801-68281890-18752014-12-0149101823Genetic diversity in Borrelia burgdorferi sensu latoAnn-Kristin Tveten0Høgskolen i ÅlesundBackground: Borrelia burgdorferi sensu lato complex comprise a number of Borrelia species related to Lyme Borreliosis (LB). Three of the human pathogenic species, Borrelia burgdorferi sensu stricto, Borrelia afzelii and Borrelia garinii are common in Europe. Human LB infection is a complex disease and the different Borrelia species display different clinical manifestations. Materials and methods: The study is based on search in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/) and global MLST databases (http://www.mlst.net/ and http://pubmlst.org/). Search keywords; “MLST, Borrelia, Genetics, Taxonomy, Host, Evolution, Lyme”. The majority of authors of the articles used are working in the major research groups that study Borrelia-MLST worldwide. Discussion: Borrelia taxonomy is in continual development and multilocus sequence typing (MLST) is one of the methods used for genetic characterization of Borrelia species. MLST is an analysis tool that provides results comparable worldwide through an online database (borrelia.mlst.net). The method is based on a set of strict criteria, which have to be met in order for the MLST to be applied in taxonomy and evolutionary studies. MLST has demonstrated a great diversity among Borrelia strains. Research indicates that the diversity among Borrelia strains can be related to determinants such as host and geographic origin. https://bioingenioren.no/fag/fag-oversiktsartikkel/genetisk-mangfold-i-borrelia-burgdorferi-sensu-lato/mlstborreliagenetic diversity |
| spellingShingle | Ann-Kristin Tveten Genetic diversity in Borrelia burgdorferi sensu lato Bioingeniøren mlst borrelia genetic diversity |
| title | Genetic diversity in Borrelia burgdorferi sensu lato |
| title_full | Genetic diversity in Borrelia burgdorferi sensu lato |
| title_fullStr | Genetic diversity in Borrelia burgdorferi sensu lato |
| title_full_unstemmed | Genetic diversity in Borrelia burgdorferi sensu lato |
| title_short | Genetic diversity in Borrelia burgdorferi sensu lato |
| title_sort | genetic diversity in borrelia burgdorferi sensu lato |
| topic | mlst borrelia genetic diversity |
| url | https://bioingenioren.no/fag/fag-oversiktsartikkel/genetisk-mangfold-i-borrelia-burgdorferi-sensu-lato/ |
| work_keys_str_mv | AT annkristintveten geneticdiversityinborreliaburgdorferisensulato |