Autoimmunity in Wiskott-Aldrich Syndrome: an unsolved enigma

Autoimmunity in Wiskott-Aldrich Syndrome: an unsolved enigma

Wiskott-Aldrich Syndrome (WAS) is a severe X-linked Primary Immunodeficiency (PID) that affects 1 to 10 out of 1 million male individuals. WAS is caused by mutations in the WAS Protein (WASP) expressing gene that leads to the absent or reduced expression of the protein. WASP is a cytoplasmic protein...

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Bibliographic Details
Main Authors: Marco eCatucci, Maria Carmina eCastiello, Francesca ePala, Marita eBosticardo, Anna eVilla
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-07-01
Series:Frontiers in Immunology
Subjects:
Autoimmunity
Wiskott-Aldrich Syndrome
T lymphocytes
B lymphocytes
Primary immunodeficiency
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00209/full

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