Disruption of the glutamate-glutamine cycle involving astrocytes in an animal model of depression for males and females
Background: Women are twice as likely as men to develop major depression (MD). The brain mechanisms underlying this sex disparity are not clear. Disruption of the glutamate-glutamine cycle has been implicated in psychiatric disturbances. This study identifies sex-based impairments in the glutamate-g...
Main Authors: | Virginie Rappeneau, Amanda Blaker, Jeff R. Petro, Bryan K. Yamamoto, Akiko Shimamoto |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2016-12-01
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Series: | Frontiers in Behavioral Neuroscience |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fnbeh.2016.00231/full |
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