Deep learning-assisted concentration gradient generation for the study of 3D cell cultures in hydrogel beads of varying stiffness

Deep learning-assisted concentration gradient generation for the study of 3D cell cultures in hydrogel beads of varying stiffness

The study of dose-response relationships underpins analytical biosciences. Droplet microfluidics platforms can automate the generation of microreactors encapsulating varying concentrations of an assay component, providing datasets across a large chemical space in a single experiment. A classical met...

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Bibliographic Details
Main Authors:	Vasileios Anagnostidis, Anuj Tiwari, Fabrice Gielen
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-04-01
Series:	Frontiers in Bioengineering and Biotechnology
Subjects:	microfluidics deep learning concentration gradient 3D cell culture object detection stiffness
Online Access:	https://www.frontiersin.org/articles/10.3389/fbioe.2024.1364553/full

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