Valproic acid induces cutaneous wound healing in vivo and enhances keratinocyte motility.
BACKGROUND: Cutaneous wound healing is a complex process involving several signaling pathways such as the Wnt and extracellular signal-regulated kinase (ERK) signaling pathways. Valproic acid (VPA) is a commonly used antiepileptic drug that acts on these signaling pathways; however, the effect of VP...
Main Authors: | Soung-Hoon Lee, Muhammad Zahoor, Jae-Kwan Hwang, Do Sik Min, Kang-Yell Choi |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3492241?pdf=render |
Similar Items
-
Keratinocyte-targeted overexpression of the glucocorticoid receptor delays cutaneous wound healing.
by: Ana Sanchis, et al.
Published: (2012-01-01) -
Hormesis: Wound healing and keratinocytes
by: Edward J. Calabrese, et al.
Published: (2022-09-01) -
Valproic acid induces hair regeneration in murine model and activates alkaline phosphatase activity in human dermal papilla cells.
by: Soung-Hoon Lee, et al.
Published: (2012-01-01) -
Pyruvate Kinase M2 Accelerates Cutaneous Wound Healing via Glycolysis and Wnt/β-Catenin Signaling
by: Eunhwan Kim, et al.
Published: (2023-07-01) -
Puerarin Improves Dexamethasone-Impaired Wound Healing In Vitro and In Vivo by Enhancing Keratinocyte Proliferation and Migration
by: Ly Thi Huong Nguyen, et al.
Published: (2021-10-01)