Spi-B Promotes the Recruitment of Tumor-Associated Macrophages via Enhancing CCL4 Expression in Lung Cancer

Spi-B Promotes the Recruitment of Tumor-Associated Macrophages via Enhancing CCL4 Expression in Lung Cancer

Tumor immune escape plays a critical role in malignant tumor progression and leads to the failure of anticancer immunotherapy. Spi-B, a lymphocyte lineage-specific Ets transcription factor, participates in mesenchymal invasion and favors metastasis in human lung cancer. However, the mechanism throug...

Full description

Bibliographic Details
Main Authors: Qiumin Huang, Junrong Liu, Shuainan Wu, Xuexi Zhang, Zengtuan Xiao, Zhe Liu, Wei Du
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Oncology
Subjects:
tumor-associated macrophages
lung cancer
CCL4
CD163
Spi-B
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.659131/full

Similar Items

Similar Items