Global burden of the COVID-19 associated patient-related delay in emergency healthcare: a panel of systematic review and meta-analyses
Abstract Background Apart from infecting a large number of people around the world and causing the death of many people, the COVID-19 pandemic seems to have changed the healthcare processes of other diseases by changing the allocation of health resources and changing people’s access or intention to...
| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2022-06-01
|
| Series: | Globalization and Health |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12992-022-00836-2 |
| _version_ | 1811247865545097216 |
|---|---|
| author | Vahid Mogharab Mahshid Ostovar Jakub Ruszkowski Syed Zohaib Maroof Hussain Rajeev Shrestha Uzair Yaqoob Poorya Aryanpoor Amir Mohammad Nikkhoo Parasta Heidari Athar Rasekh Jahromi Esmaeil Rayatdoost Anwar Ali Farshid Javdani Roohie Farzaneh Aref Ghanaatpisheh Seyed Reza Habibzadeh Mahdi Foroughian Sayyed Reza Ahmadi Reza Akhavan Bita Abbasi Behzad Shahi Arman Hakemi Ehsan Bolvardi Farhad Bagherian Mahsa Motamed Sina Taherzadeh Boroujeni Sheida Jamalnia Amir Mangouri Maryam Paydar Neda Mehrasa Dorna Shirali Francesco Sanmarchi Ayesha Saeed Narges Azari Jafari Ali Babou Navid Kalani Naser Hatami |
| author_facet | Vahid Mogharab Mahshid Ostovar Jakub Ruszkowski Syed Zohaib Maroof Hussain Rajeev Shrestha Uzair Yaqoob Poorya Aryanpoor Amir Mohammad Nikkhoo Parasta Heidari Athar Rasekh Jahromi Esmaeil Rayatdoost Anwar Ali Farshid Javdani Roohie Farzaneh Aref Ghanaatpisheh Seyed Reza Habibzadeh Mahdi Foroughian Sayyed Reza Ahmadi Reza Akhavan Bita Abbasi Behzad Shahi Arman Hakemi Ehsan Bolvardi Farhad Bagherian Mahsa Motamed Sina Taherzadeh Boroujeni Sheida Jamalnia Amir Mangouri Maryam Paydar Neda Mehrasa Dorna Shirali Francesco Sanmarchi Ayesha Saeed Narges Azari Jafari Ali Babou Navid Kalani Naser Hatami |
| author_sort | Vahid Mogharab |
| collection | DOAJ |
| description | Abstract Background Apart from infecting a large number of people around the world and causing the death of many people, the COVID-19 pandemic seems to have changed the healthcare processes of other diseases by changing the allocation of health resources and changing people’s access or intention to healthcare systems. Objective To compare the incidence of endpoints marking delayed healthcare seeking in medical emergencies, before and during the pandemic. Methods Based on a PICO model, medical emergency conditions that need timely intervention was selected to be evaluated as separate panels. In a systematic literature review, PubMed was quarried for each panel for studies comparing the incidence of various medical emergencies before and during the COVID-19 pandemic. Markers of failure/disruption of treatment due to delayed referral were included in the meta-analysis for each panel. Result There was a statistically significant increased pooled median time of symptom onset to admission of the acute coronary syndrome (ACS) patients; an increased rate of vasospasm of aneurismal subarachnoid hemorrhage; and perforation rate in acute appendicitis; diabetic ketoacidosis presentation rate among Type 1 Diabetes Mellitus patients; and rate of orchiectomy among testicular torsion patients in comparison of pre-COVID-19 with COVID-19 cohorts; while there were no significant changes in the event rate of ruptured ectopic pregnancy and median time of symptom onset to admission in the cerebrovascular accident (CVA) patients. Conclusions COVID-19 has largely disrupted the referral of patients for emergency medical care and patient-related delayed care should be addressed as a major health threat. |
| first_indexed | 2024-04-12T15:16:59Z |
| format | Article |
| id | doaj.art-061ad722206a475c9cef897037b9a857 |
| institution | Directory Open Access Journal |
| issn | 1744-8603 |
| language | English |
| last_indexed | 2024-04-12T15:16:59Z |
| publishDate | 2022-06-01 |
| publisher | BMC |
| record_format | Article |
| series | Globalization and Health |
| spelling | doaj.art-061ad722206a475c9cef897037b9a8572022-12-22T03:27:35ZengBMCGlobalization and Health1744-86032022-06-0118111810.1186/s12992-022-00836-2Global burden of the COVID-19 associated patient-related delay in emergency healthcare: a panel of systematic review and meta-analysesVahid Mogharab0Mahshid Ostovar1Jakub Ruszkowski2Syed Zohaib Maroof Hussain3Rajeev Shrestha4Uzair Yaqoob5Poorya Aryanpoor6Amir Mohammad Nikkhoo7Parasta Heidari8Athar Rasekh Jahromi9Esmaeil Rayatdoost10Anwar Ali11Farshid Javdani12Roohie Farzaneh13Aref Ghanaatpisheh14Seyed Reza Habibzadeh15Mahdi Foroughian16Sayyed Reza Ahmadi17Reza Akhavan18Bita Abbasi19Behzad Shahi20Arman Hakemi21Ehsan Bolvardi22Farhad Bagherian23Mahsa Motamed24Sina Taherzadeh Boroujeni25Sheida Jamalnia26Amir Mangouri27Maryam Paydar28Neda Mehrasa29Dorna Shirali30Francesco Sanmarchi31Ayesha Saeed32Narges Azari Jafari33Ali Babou34Navid Kalani35Naser Hatami36Department of Pediatrics, Jahrom University of Medical SciencesResearch Center for Non-Communicable Diseases, Jahrom University of Medical SciencesDepartment of Nephrology, Transplantology and Internal Medicine, Faculty of Medicine, Medical University of GdańskST1/Clinical Teaching Fellow, Norfolk and Norwich University HospitalPalliative Care and Chronic Disease Unit, Green Pasteur HospitalPostgraduate trainee, Surgical Department, Hamdard University Hospital KarachiResearch Center for Non-Communicable Diseases, Jahrom University of Medical SciencesResearch Center for Non-Communicable Diseases, Jahrom University of Medical SciencesResearch Center for Non-Communicable Diseases, Jahrom University of Medical SciencesResearch Center for Non-Communicable Diseases, Jahrom University of Medical SciencesResearch Center for Non-Communicable Diseases, Jahrom University of Medical SciencesDepartment of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South UniversityResearch Center for Non-Communicable Diseases, Jahrom University of Medical SciencesDepartment of Emergency Medicine, Faculty of Medicine, Mashhad University of Medical SciencesResearch Center for Non-Communicable Diseases, Jahrom University of Medical SciencesDepartment of Emergency Medicine, Faculty of Medicine, Mashhad University of Medical SciencesDepartment of Emergency Medicine, Faculty of Medicine, Mashhad University of Medical SciencesDepartment of Emergency Medicine, Faculty of Medicine, Mashhad University of Medical SciencesDepartment of Emergency Medicine, Faculty of Medicine, Mashhad University of Medical SciencesDepartment of Radiology, Faculty of Medicine, Mashhad University of Medical sciencesDepartment of Emergency Medicine, Faculty of Medicine, Zahedan University of Medical SciencesDepartment of Emergency Medicine, Faculty of Medicine, Mashhad University of Medical SciencesDepartment of Emergency Medicine, Faculty of Medicine, Mashhad University of Medical SciencesDepartment of Emergency Medicine, Babol University of Medical SciencesDepartment of Psychiatry, Tehran University of Medical SciencesDepartment of Psychiatry, Tehran University of Medical SciencesMedical Journalism Department, Shiraz University of Medical SciencesFellowship of Vascular Surgery and Endovascular Therapy, Division of Vascular Surgery and Endovascular Therapy, Department of General Surgery, Sina Hospital, Tehran University of Medical SciencesResearch Center for Non-Communicable Diseases, Jahrom University of Medical SciencesShiraz Azad University, Dental BranchShiraz Azad University, Dental BranchDepartment of Biomedical and Neuromotor Sciences, Alma Mater Studiorum, University of BolognaDepartment of Biochemistry, Government College UniversityNeuroscience Research Department Center, Kashan University of Medical SciencePharmaceutical Sciences Department, College of Pharmacy, Gulf Medical UniversityResearch Center for Non-Communicable Diseases, Jahrom University of Medical SciencesResearch Center for Non-Communicable Diseases, Jahrom University of Medical SciencesAbstract Background Apart from infecting a large number of people around the world and causing the death of many people, the COVID-19 pandemic seems to have changed the healthcare processes of other diseases by changing the allocation of health resources and changing people’s access or intention to healthcare systems. Objective To compare the incidence of endpoints marking delayed healthcare seeking in medical emergencies, before and during the pandemic. Methods Based on a PICO model, medical emergency conditions that need timely intervention was selected to be evaluated as separate panels. In a systematic literature review, PubMed was quarried for each panel for studies comparing the incidence of various medical emergencies before and during the COVID-19 pandemic. Markers of failure/disruption of treatment due to delayed referral were included in the meta-analysis for each panel. Result There was a statistically significant increased pooled median time of symptom onset to admission of the acute coronary syndrome (ACS) patients; an increased rate of vasospasm of aneurismal subarachnoid hemorrhage; and perforation rate in acute appendicitis; diabetic ketoacidosis presentation rate among Type 1 Diabetes Mellitus patients; and rate of orchiectomy among testicular torsion patients in comparison of pre-COVID-19 with COVID-19 cohorts; while there were no significant changes in the event rate of ruptured ectopic pregnancy and median time of symptom onset to admission in the cerebrovascular accident (CVA) patients. Conclusions COVID-19 has largely disrupted the referral of patients for emergency medical care and patient-related delayed care should be addressed as a major health threat.https://doi.org/10.1186/s12992-022-00836-2COVID-19SARS-COV-2PandemicEmergency department |
| spellingShingle | Vahid Mogharab Mahshid Ostovar Jakub Ruszkowski Syed Zohaib Maroof Hussain Rajeev Shrestha Uzair Yaqoob Poorya Aryanpoor Amir Mohammad Nikkhoo Parasta Heidari Athar Rasekh Jahromi Esmaeil Rayatdoost Anwar Ali Farshid Javdani Roohie Farzaneh Aref Ghanaatpisheh Seyed Reza Habibzadeh Mahdi Foroughian Sayyed Reza Ahmadi Reza Akhavan Bita Abbasi Behzad Shahi Arman Hakemi Ehsan Bolvardi Farhad Bagherian Mahsa Motamed Sina Taherzadeh Boroujeni Sheida Jamalnia Amir Mangouri Maryam Paydar Neda Mehrasa Dorna Shirali Francesco Sanmarchi Ayesha Saeed Narges Azari Jafari Ali Babou Navid Kalani Naser Hatami Global burden of the COVID-19 associated patient-related delay in emergency healthcare: a panel of systematic review and meta-analyses Globalization and Health COVID-19 SARS-COV-2 Pandemic Emergency department |
| title | Global burden of the COVID-19 associated patient-related delay in emergency healthcare: a panel of systematic review and meta-analyses |
| title_full | Global burden of the COVID-19 associated patient-related delay in emergency healthcare: a panel of systematic review and meta-analyses |
| title_fullStr | Global burden of the COVID-19 associated patient-related delay in emergency healthcare: a panel of systematic review and meta-analyses |
| title_full_unstemmed | Global burden of the COVID-19 associated patient-related delay in emergency healthcare: a panel of systematic review and meta-analyses |
| title_short | Global burden of the COVID-19 associated patient-related delay in emergency healthcare: a panel of systematic review and meta-analyses |
| title_sort | global burden of the covid 19 associated patient related delay in emergency healthcare a panel of systematic review and meta analyses |
| topic | COVID-19 SARS-COV-2 Pandemic Emergency department |
| url | https://doi.org/10.1186/s12992-022-00836-2 |
| work_keys_str_mv | AT vahidmogharab globalburdenofthecovid19associatedpatientrelateddelayinemergencyhealthcareapanelofsystematicreviewandmetaanalyses AT mahshidostovar globalburdenofthecovid19associatedpatientrelateddelayinemergencyhealthcareapanelofsystematicreviewandmetaanalyses AT jakubruszkowski globalburdenofthecovid19associatedpatientrelateddelayinemergencyhealthcareapanelofsystematicreviewandmetaanalyses AT syedzohaibmaroofhussain globalburdenofthecovid19associatedpatientrelateddelayinemergencyhealthcareapanelofsystematicreviewandmetaanalyses AT rajeevshrestha globalburdenofthecovid19associatedpatientrelateddelayinemergencyhealthcareapanelofsystematicreviewandmetaanalyses AT uzairyaqoob globalburdenofthecovid19associatedpatientrelateddelayinemergencyhealthcareapanelofsystematicreviewandmetaanalyses AT pooryaaryanpoor globalburdenofthecovid19associatedpatientrelateddelayinemergencyhealthcareapanelofsystematicreviewandmetaanalyses AT amirmohammadnikkhoo globalburdenofthecovid19associatedpatientrelateddelayinemergencyhealthcareapanelofsystematicreviewandmetaanalyses AT parastaheidari globalburdenofthecovid19associatedpatientrelateddelayinemergencyhealthcareapanelofsystematicreviewandmetaanalyses AT atharrasekhjahromi globalburdenofthecovid19associatedpatientrelateddelayinemergencyhealthcareapanelofsystematicreviewandmetaanalyses AT esmaeilrayatdoost globalburdenofthecovid19associatedpatientrelateddelayinemergencyhealthcareapanelofsystematicreviewandmetaanalyses AT anwarali globalburdenofthecovid19associatedpatientrelateddelayinemergencyhealthcareapanelofsystematicreviewandmetaanalyses AT farshidjavdani globalburdenofthecovid19associatedpatientrelateddelayinemergencyhealthcareapanelofsystematicreviewandmetaanalyses AT roohiefarzaneh globalburdenofthecovid19associatedpatientrelateddelayinemergencyhealthcareapanelofsystematicreviewandmetaanalyses AT arefghanaatpisheh globalburdenofthecovid19associatedpatientrelateddelayinemergencyhealthcareapanelofsystematicreviewandmetaanalyses AT seyedrezahabibzadeh globalburdenofthecovid19associatedpatientrelateddelayinemergencyhealthcareapanelofsystematicreviewandmetaanalyses AT mahdiforoughian globalburdenofthecovid19associatedpatientrelateddelayinemergencyhealthcareapanelofsystematicreviewandmetaanalyses AT sayyedrezaahmadi globalburdenofthecovid19associatedpatientrelateddelayinemergencyhealthcareapanelofsystematicreviewandmetaanalyses AT rezaakhavan globalburdenofthecovid19associatedpatientrelateddelayinemergencyhealthcareapanelofsystematicreviewandmetaanalyses AT bitaabbasi globalburdenofthecovid19associatedpatientrelateddelayinemergencyhealthcareapanelofsystematicreviewandmetaanalyses AT behzadshahi globalburdenofthecovid19associatedpatientrelateddelayinemergencyhealthcareapanelofsystematicreviewandmetaanalyses AT armanhakemi globalburdenofthecovid19associatedpatientrelateddelayinemergencyhealthcareapanelofsystematicreviewandmetaanalyses AT ehsanbolvardi globalburdenofthecovid19associatedpatientrelateddelayinemergencyhealthcareapanelofsystematicreviewandmetaanalyses AT farhadbagherian globalburdenofthecovid19associatedpatientrelateddelayinemergencyhealthcareapanelofsystematicreviewandmetaanalyses AT mahsamotamed globalburdenofthecovid19associatedpatientrelateddelayinemergencyhealthcareapanelofsystematicreviewandmetaanalyses AT sinataherzadehboroujeni globalburdenofthecovid19associatedpatientrelateddelayinemergencyhealthcareapanelofsystematicreviewandmetaanalyses AT sheidajamalnia globalburdenofthecovid19associatedpatientrelateddelayinemergencyhealthcareapanelofsystematicreviewandmetaanalyses AT amirmangouri globalburdenofthecovid19associatedpatientrelateddelayinemergencyhealthcareapanelofsystematicreviewandmetaanalyses AT maryampaydar globalburdenofthecovid19associatedpatientrelateddelayinemergencyhealthcareapanelofsystematicreviewandmetaanalyses AT nedamehrasa globalburdenofthecovid19associatedpatientrelateddelayinemergencyhealthcareapanelofsystematicreviewandmetaanalyses AT dornashirali globalburdenofthecovid19associatedpatientrelateddelayinemergencyhealthcareapanelofsystematicreviewandmetaanalyses AT francescosanmarchi globalburdenofthecovid19associatedpatientrelateddelayinemergencyhealthcareapanelofsystematicreviewandmetaanalyses AT ayeshasaeed globalburdenofthecovid19associatedpatientrelateddelayinemergencyhealthcareapanelofsystematicreviewandmetaanalyses AT nargesazarijafari globalburdenofthecovid19associatedpatientrelateddelayinemergencyhealthcareapanelofsystematicreviewandmetaanalyses AT alibabou globalburdenofthecovid19associatedpatientrelateddelayinemergencyhealthcareapanelofsystematicreviewandmetaanalyses AT navidkalani globalburdenofthecovid19associatedpatientrelateddelayinemergencyhealthcareapanelofsystematicreviewandmetaanalyses AT naserhatami globalburdenofthecovid19associatedpatientrelateddelayinemergencyhealthcareapanelofsystematicreviewandmetaanalyses |