Prevalence of pulmonary thromboembolism in nephrotic syndrome patients: A systematic review and meta-analysis
This study was aimed to assess the prevalence of pulmonary thromboembolism in patients with nephrotic syndrome. An electronic search was conducted through nine electronic databases for selection of relevant articles reporting the prevalence of pulmonary thromboembolism in patients with nephrotic syn...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2020-01-01
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| Series: | Journal of Family Medicine and Primary Care |
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| Online Access: | http://www.jfmpc.com/article.asp?issn=2249-4863;year=2020;volume=9;issue=2;spage=497;epage=501;aulast=Leslom |
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| author | Abdullah Nasser Leslom Ziyad Mohammed Saeed Alrawiah Ahmed Mohammed Ahmed Al-Asmari Moneer Dhafer Ali Alqashaneen Abdulaziz Oudah Tami Alahmari Hamuod Oudah Bin Tami Al-Ahmari |
| author_facet | Abdullah Nasser Leslom Ziyad Mohammed Saeed Alrawiah Ahmed Mohammed Ahmed Al-Asmari Moneer Dhafer Ali Alqashaneen Abdulaziz Oudah Tami Alahmari Hamuod Oudah Bin Tami Al-Ahmari |
| author_sort | Abdullah Nasser Leslom |
| collection | DOAJ |
| description | This study was aimed to assess the prevalence of pulmonary thromboembolism in patients with nephrotic syndrome. An electronic search was conducted through nine electronic databases for selection of relevant articles reporting the prevalence of pulmonary thromboembolism in patients with nephrotic syndrome. National Institute of Health was used to assess the quality of each study. Meta-analysis was used to pool the results. Of total 2267 reports screened, we finally included 11 studies including five retrospective cohorts, four prospective cohorts, and two case series studies. Out of these, ten articles were eligible for meta-analysis. The overall prevalence was 7.93% with 95% CI of 4.27 to 14.73. However, a significant heterogeneity (P < 0.001) was observed with I2= 96% and τ2= 0.899. Moreover, Egger's regression test showed a significant risk of bias (P = 0.006). Patients with nephrotic syndrome are prone to pulmonary embolism, therefore early management is critical to decreasing mortality burden. |
| first_indexed | 2024-12-12T15:59:01Z |
| format | Article |
| id | doaj.art-061dd330e55a40a0ad3fccf765575b62 |
| institution | Directory Open Access Journal |
| issn | 2249-4863 |
| language | English |
| last_indexed | 2024-12-12T15:59:01Z |
| publishDate | 2020-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Family Medicine and Primary Care |
| spelling | doaj.art-061dd330e55a40a0ad3fccf765575b622022-12-22T00:19:25ZengWolters Kluwer Medknow PublicationsJournal of Family Medicine and Primary Care2249-48632020-01-019249750110.4103/jfmpc.jfmpc_1076_19Prevalence of pulmonary thromboembolism in nephrotic syndrome patients: A systematic review and meta-analysisAbdullah Nasser LeslomZiyad Mohammed Saeed AlrawiahAhmed Mohammed Ahmed Al-AsmariMoneer Dhafer Ali AlqashaneenAbdulaziz Oudah Tami AlahmariHamuod Oudah Bin Tami Al-AhmariThis study was aimed to assess the prevalence of pulmonary thromboembolism in patients with nephrotic syndrome. An electronic search was conducted through nine electronic databases for selection of relevant articles reporting the prevalence of pulmonary thromboembolism in patients with nephrotic syndrome. National Institute of Health was used to assess the quality of each study. Meta-analysis was used to pool the results. Of total 2267 reports screened, we finally included 11 studies including five retrospective cohorts, four prospective cohorts, and two case series studies. Out of these, ten articles were eligible for meta-analysis. The overall prevalence was 7.93% with 95% CI of 4.27 to 14.73. However, a significant heterogeneity (P < 0.001) was observed with I2= 96% and τ2= 0.899. Moreover, Egger's regression test showed a significant risk of bias (P = 0.006). Patients with nephrotic syndrome are prone to pulmonary embolism, therefore early management is critical to decreasing mortality burden.http://www.jfmpc.com/article.asp?issn=2249-4863;year=2020;volume=9;issue=2;spage=497;epage=501;aulast=Leslomglomerulosclerosisnephrotic syndromeproteinuriapulmonary thromboembolism |
| spellingShingle | Abdullah Nasser Leslom Ziyad Mohammed Saeed Alrawiah Ahmed Mohammed Ahmed Al-Asmari Moneer Dhafer Ali Alqashaneen Abdulaziz Oudah Tami Alahmari Hamuod Oudah Bin Tami Al-Ahmari Prevalence of pulmonary thromboembolism in nephrotic syndrome patients: A systematic review and meta-analysis Journal of Family Medicine and Primary Care glomerulosclerosis nephrotic syndrome proteinuria pulmonary thromboembolism |
| title | Prevalence of pulmonary thromboembolism in nephrotic syndrome patients: A systematic review and meta-analysis |
| title_full | Prevalence of pulmonary thromboembolism in nephrotic syndrome patients: A systematic review and meta-analysis |
| title_fullStr | Prevalence of pulmonary thromboembolism in nephrotic syndrome patients: A systematic review and meta-analysis |
| title_full_unstemmed | Prevalence of pulmonary thromboembolism in nephrotic syndrome patients: A systematic review and meta-analysis |
| title_short | Prevalence of pulmonary thromboembolism in nephrotic syndrome patients: A systematic review and meta-analysis |
| title_sort | prevalence of pulmonary thromboembolism in nephrotic syndrome patients a systematic review and meta analysis |
| topic | glomerulosclerosis nephrotic syndrome proteinuria pulmonary thromboembolism |
| url | http://www.jfmpc.com/article.asp?issn=2249-4863;year=2020;volume=9;issue=2;spage=497;epage=501;aulast=Leslom |
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