Plant-Produced Glycosylated and In Vivo Deglycosylated Receptor Binding Domain Proteins of SARS-CoV-2 Induce Potent Neutralizing Responses in Mice

Plant-Produced Glycosylated and In Vivo Deglycosylated Receptor Binding Domain Proteins of SARS-CoV-2 Induce Potent Neutralizing Responses in Mice

The COVID-19 pandemic, caused by SARS-CoV-2, has rapidly spread to more than 222 countries and has put global public health at high risk. The world urgently needs cost-effective and safe SARS-CoV-2 vaccines, antiviral, and therapeutic drugs to control it. In this study, we engineered the receptor bi...

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Bibliographic Details
Main Authors: Tarlan Mamedov, Damla Yuksel, Merve Ilgın, Irem Gurbuzaslan, Burcu Gulec, Hazel Yetiskin, Muhammet Ali Uygut, Shaikh Terkis Islam Pavel, Aykut Ozdarendeli, Gulshan Mammadova, Deniz Say, Gulnara Hasanova
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Viruses
Subjects:
COVID-19
SARS-CoV-2
spike protein
receptor binding domain (RBD) vaccine
plant
transient expression system
Online Access:https://www.mdpi.com/1999-4915/13/8/1595

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