Brain uptake of hydroxytyrosol and its main circulating metabolites: Protective potential in neuronal cells

Brain uptake of hydroxytyrosol and its main circulating metabolites: Protective potential in neuronal cells

Hydroxytyrosol (HT) and oleuropein derivatives are the main phenolic compounds in virgin olive oil (VOO). After VOO intake, HT is extensively metabolized being hydroxytyrosol-sulphate (HT-S) and hydroxytyrosol-acetate sulphate (HT-AC-S) the main circulating metabolites detected in human plasma. The...

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Bibliographic Details
Main Authors: María-Carmen López de las Hazas, Joana Godinho-Pereira, Alba Macià, A. Filipa Almeida, M. Rita Ventura, Maria-José Motilva, Cláudia N. Santos
Format: Article
Language:English
Published: Elsevier 2018-07-01
Series:Journal of Functional Foods
Subjects:
Bioactivity
Dopaminergic cells
Hydroxytyrosol
Neurodegeneration
Phase-II metabolites
Sulphation
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464618301671

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