Selection of appropriate dapsone and poly(1-vinylpyrrolidone-co-vinyl acetate) ratios for the preparation of amorphous solid dispersions

Selection of appropriate dapsone and poly(1-vinylpyrrolidone-co-vinyl acetate) ratios for the preparation of amorphous solid dispersions

Drug-polymer miscibility is a critical requirement for the efficient design and development of amorphous solid dispersions. The objective of the current study was to determine the miscibility between dapsone (DAP) and poly(1-vinylpyrrolidone-co-vinyl acetate) (PVP-VA) through theoretical and experim...

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Bibliographic Details
Main Authors:	Dinesh Choudhury, Upadhyayula Suryanarayana Murty, Subham Banerjee
Format:	Article
Language:	English
Published:	Elsevier 2023-03-01
Series:	Heliyon
Subjects:	Miscibility Solubility parameter Interaction parameter Gibbs free energy Thermodynamic phase diagram
Online Access:	http://www.sciencedirect.com/science/article/pii/S2405844023013749

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