Development of an optogenetic toolkit for neural circuit dissection in squirrel monkeys

Abstract Optogenetic tools have opened a rich experimental landscape for understanding neural function and disease. Here, we present the first validation of eight optogenetic constructs driven by recombinant adeno-associated virus (AAV) vectors and a WGA-Cre based dual injection strategy for project...

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Bibliographic Details
Main Authors: Daniel J. O’Shea, Paul Kalanithi, Emily A. Ferenczi, Brian Hsueh, Chandramouli Chandrasekaran, Werapong Goo, Ilka Diester, Charu Ramakrishnan, Matthew T. Kaufman, Stephen I. Ryu, Kristen W. Yeom, Karl Deisseroth, Krishna V. Shenoy
Format: Article
Language:English
Published: Nature Portfolio 2018-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-018-24362-7