Abnormal signal pathways and tumor heterogeneity in osteosarcoma

Abnormal signal pathways and tumor heterogeneity in osteosarcoma

Abstract Background Osteosarcoma (OS) is the most frequent and aggressive primary malignant sarcoma among adolescents and chemotherapy has not substantially progressed for decades. New insights into OS development and therapeutic strategies are urgently needed. Methods We analyzed integrated single-...

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Bibliographic Details
Main Authors: Yifeng Sun, Chunming Zhang, Qiongxuan Fang, Wenqiang Zhang, Wei Liu
Format: Article
Language:English
Published: BMC 2023-02-01
Series:Journal of Translational Medicine
Subjects:
Osteosarcoma
Abnormal signal pathway
Chemotherapy
Oncocyte heterogeneity
Online Access:https://doi.org/10.1186/s12967-023-03961-7

Internet

https://doi.org/10.1186/s12967-023-03961-7

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