Stochastic fluctuations promote ordered pattern formation of cells in the Notch-Delta signaling pathway.

The Notch-Delta signaling pathway mediates cell differentiation implicated in many regulatory processes including spatiotemporal patterning in tissues by promoting alternate cell fates between neighboring cells. At the multicellular level, this "lateral inhibition" principle leads to check...

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Bibliographic Details
Main Authors: Madeline Galbraith, Federico Bocci, José N Onuchic
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-07-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1010306

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