Stochastic fluctuations promote ordered pattern formation of cells in the Notch-Delta signaling pathway.
The Notch-Delta signaling pathway mediates cell differentiation implicated in many regulatory processes including spatiotemporal patterning in tissues by promoting alternate cell fates between neighboring cells. At the multicellular level, this "lateral inhibition" principle leads to check...
Main Authors: | Madeline Galbraith, Federico Bocci, José N Onuchic |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2022-07-01
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Series: | PLoS Computational Biology |
Online Access: | https://doi.org/10.1371/journal.pcbi.1010306 |
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