Expression of IL-37 Induces a Regulatory T-Cell-like Phenotype and Function in Jurkat Cells

Expression of IL-37 Induces a Regulatory T-Cell-like Phenotype and Function in Jurkat Cells

The anti-inflammatory cytokine interleukin-37 (IL-37) plays a key role in inhibiting innate and adaptive immunity. Past results have shown that IL-37 is elevated in human Treg cells compared to other T cell subsets and contributes to enhancing the Treg transcription factor, forkhead box protein P3 (...

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Bibliographic Details
Main Authors: Douglas Grant Osborne, Joanne Domenico, Mayumi Fujita
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Cells
Subjects:
IL-37
regulatory T cell
Treg
FOXP3
Jurkat
Online Access:https://www.mdpi.com/2073-4409/11/16/2565

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