Development of High Cell Density Cultivation Strategies for Improved Medium Chain Length Polyhydroxyalkanoate Productivity Using <i>Pseudomonas putida</i> LS46

Development of High Cell Density Cultivation Strategies for Improved Medium Chain Length Polyhydroxyalkanoate Productivity Using <i>Pseudomonas putida</i> LS46

High cell density (HCD) fed-batch cultures are widely perceived as a requisite for high-productivity polyhydroxyalkanoate (PHA) cultivation processes. In this work, a reactive pulse feed strategy (based on real-time CO<sub>2</sub> or dissolved oxygen (DO) measurements as feedback variabl...

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Bibliographic Details
Main Authors: Warren Blunt, Christopher Dartiailh, Richard Sparling, Daniel J. Gapes, David B. Levin, Nazim Cicek
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Bioengineering
Subjects:
polyhydroxyalkanoates
fed-batch
productivity
<i>pseudomonas</i>
bioreactor
microaerophilic
Online Access:https://www.mdpi.com/2306-5354/6/4/89

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