Non-Cationic RGD-Containing Protein Nanocarrier for Tumor-Targeted siRNA Delivery

Despite the recent successes in siRNA therapeutics, targeted delivery beyond the liver remains the major hurdle for the widespread application of siRNA in vivo. Current cationic liposome or polymer-based delivery agents are restricted to the liver and suffer from off-target effects, poor clearance,...

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Hlavní autoři: Xiaolin Yu, Lu Xue, Jing Zhao, Shuhua Zhao, Daqing Wu, Hong Yan Liu
Médium: Článek
Jazyk:English
Vydáno: MDPI AG 2021-12-01
Edice:Pharmaceutics
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On-line přístup:https://www.mdpi.com/1999-4923/13/12/2182