Recent Advances in pH- or/and Photo-Responsive Nanovehicles
The combination of nanotechnology and chemotherapy has resulted in more effective drug design via the development of nanomaterial-based drug delivery systems (DDSs) for tumor targeting. Stimulus-responsive DDSs in response to internal or external signals can offer precisely controlled delivery of pr...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2021-05-01
|
| Series: | Pharmaceutics |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1999-4923/13/5/725 |
| _version_ | 1797533992171339776 |
|---|---|
| author | Yuseon Shin Patihul Husni Kioh Kang Dayoon Lee Sehwa Lee Eunseong Lee Yuseok Youn Kyungtaek Oh |
| author_facet | Yuseon Shin Patihul Husni Kioh Kang Dayoon Lee Sehwa Lee Eunseong Lee Yuseok Youn Kyungtaek Oh |
| author_sort | Yuseon Shin |
| collection | DOAJ |
| description | The combination of nanotechnology and chemotherapy has resulted in more effective drug design via the development of nanomaterial-based drug delivery systems (DDSs) for tumor targeting. Stimulus-responsive DDSs in response to internal or external signals can offer precisely controlled delivery of preloaded therapeutics. Among the various DDSs, the photo-triggered system improves the efficacy and safety of treatment through spatiotemporal manipulation of light. Additionally, pH-induced delivery is one of the most widely studied strategies for targeting the acidic micro-environment of solid tumors. Accordingly, in this review, we discuss representative strategies for designing DDSs using light as an exogenous signal or pH as an endogenous trigger. |
| first_indexed | 2024-03-10T11:23:31Z |
| format | Article |
| id | doaj.art-0633dbe89ca1438faca87f90a212c996 |
| institution | Directory Open Access Journal |
| issn | 1999-4923 |
| language | English |
| last_indexed | 2024-03-10T11:23:31Z |
| publishDate | 2021-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Pharmaceutics |
| spelling | doaj.art-0633dbe89ca1438faca87f90a212c9962023-11-21T19:49:17ZengMDPI AGPharmaceutics1999-49232021-05-0113572510.3390/pharmaceutics13050725Recent Advances in pH- or/and Photo-Responsive NanovehiclesYuseon Shin0Patihul Husni1Kioh Kang2Dayoon Lee3Sehwa Lee4Eunseong Lee5Yuseok Youn6Kyungtaek Oh7Department of Global Innovative Drugs, The Graduate School of Chung-Ang University and College of Pharmacy, Chung-Ang University, 221 Heukseok-dong, Seoul 06974, KoreaDepartment of Global Innovative Drugs, The Graduate School of Chung-Ang University and College of Pharmacy, Chung-Ang University, 221 Heukseok-dong, Seoul 06974, KoreaDepartment of Global Innovative Drugs, The Graduate School of Chung-Ang University and College of Pharmacy, Chung-Ang University, 221 Heukseok-dong, Seoul 06974, KoreaDepartment of Global Innovative Drugs, The Graduate School of Chung-Ang University and College of Pharmacy, Chung-Ang University, 221 Heukseok-dong, Seoul 06974, KoreaDepartment of Global Innovative Drugs, The Graduate School of Chung-Ang University and College of Pharmacy, Chung-Ang University, 221 Heukseok-dong, Seoul 06974, KoreaDivision of Biotechnology, The Catholic University of Korea, Bucheon 14662, KoreaSchool of Pharmacy, Sungkyunkwan University, Suwon 16419, KoreaDepartment of Global Innovative Drugs, The Graduate School of Chung-Ang University and College of Pharmacy, Chung-Ang University, 221 Heukseok-dong, Seoul 06974, KoreaThe combination of nanotechnology and chemotherapy has resulted in more effective drug design via the development of nanomaterial-based drug delivery systems (DDSs) for tumor targeting. Stimulus-responsive DDSs in response to internal or external signals can offer precisely controlled delivery of preloaded therapeutics. Among the various DDSs, the photo-triggered system improves the efficacy and safety of treatment through spatiotemporal manipulation of light. Additionally, pH-induced delivery is one of the most widely studied strategies for targeting the acidic micro-environment of solid tumors. Accordingly, in this review, we discuss representative strategies for designing DDSs using light as an exogenous signal or pH as an endogenous trigger.https://www.mdpi.com/1999-4923/13/5/725chemotherapynanovehicleslightpHstimuliphotothermal |
| spellingShingle | Yuseon Shin Patihul Husni Kioh Kang Dayoon Lee Sehwa Lee Eunseong Lee Yuseok Youn Kyungtaek Oh Recent Advances in pH- or/and Photo-Responsive Nanovehicles Pharmaceutics chemotherapy nanovehicles light pH stimuli photothermal |
| title | Recent Advances in pH- or/and Photo-Responsive Nanovehicles |
| title_full | Recent Advances in pH- or/and Photo-Responsive Nanovehicles |
| title_fullStr | Recent Advances in pH- or/and Photo-Responsive Nanovehicles |
| title_full_unstemmed | Recent Advances in pH- or/and Photo-Responsive Nanovehicles |
| title_short | Recent Advances in pH- or/and Photo-Responsive Nanovehicles |
| title_sort | recent advances in ph or and photo responsive nanovehicles |
| topic | chemotherapy nanovehicles light pH stimuli photothermal |
| url | https://www.mdpi.com/1999-4923/13/5/725 |
| work_keys_str_mv | AT yuseonshin recentadvancesinphorandphotoresponsivenanovehicles AT patihulhusni recentadvancesinphorandphotoresponsivenanovehicles AT kiohkang recentadvancesinphorandphotoresponsivenanovehicles AT dayoonlee recentadvancesinphorandphotoresponsivenanovehicles AT sehwalee recentadvancesinphorandphotoresponsivenanovehicles AT eunseonglee recentadvancesinphorandphotoresponsivenanovehicles AT yuseokyoun recentadvancesinphorandphotoresponsivenanovehicles AT kyungtaekoh recentadvancesinphorandphotoresponsivenanovehicles |