Practice parameters in management of status epileptics
Status epilepticus (SE) is an emergency neurological problem, more common in the developing countries due to high incidence of infection, stroke and head injury. The protocol for management of SE is intravenous benzodiazepine, followed by phenytoin, valproate (VPA) and phenobarbitone and if uncontro...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2014-01-01
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| Series: | Annals of Indian Academy of Neurology |
| Subjects: | |
| Online Access: | http://www.annalsofian.org/article.asp?issn=0972-2327;year=2014;volume=17;issue=5;spage=27;epage=31;aulast=Misra |
| _version_ | 1818021644107513856 |
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| author | Usha Kant Misra Jayantee Kalita Sanjeev Kumar Bhoi |
| author_facet | Usha Kant Misra Jayantee Kalita Sanjeev Kumar Bhoi |
| author_sort | Usha Kant Misra |
| collection | DOAJ |
| description | Status epilepticus (SE) is an emergency neurological problem, more common in the developing countries due to high incidence of infection, stroke and head injury. The protocol for management of SE is intravenous benzodiazepine, followed by phenytoin, valproate (VPA) and phenobarbitone and if uncontrolled general anesthesia (GA). World Federation of Neurology recommends special guidelines for resource poor countries. Use of GA results in hypotension and respiratory depression needing intensive care management. There is a paucity of intensive care facilities hence the recommended antiepileptic drugs (AEDs) which have inherent toxicity of hypotension and respiratory failure cannot be given safely. Under these situations AEDs such as VPA, levetiracetam and lacosamide may be evaluated in SE because of cardiovascular and respiratory safety profile. In this review, the limitations of existing guidelines in the developing countries have been discussed and a way forward has been suggested. |
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| format | Article |
| id | doaj.art-063bf8344df743b19b6e2d658a90595f |
| institution | Directory Open Access Journal |
| issn | 0972-2327 1998-3549 |
| language | English |
| last_indexed | 2024-04-14T08:20:42Z |
| publishDate | 2014-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Annals of Indian Academy of Neurology |
| spelling | doaj.art-063bf8344df743b19b6e2d658a90595f2022-12-22T02:04:12ZengWolters Kluwer Medknow PublicationsAnnals of Indian Academy of Neurology0972-23271998-35492014-01-01175273110.4103/0972-2327.128646Practice parameters in management of status epilepticsUsha Kant MisraJayantee KalitaSanjeev Kumar BhoiStatus epilepticus (SE) is an emergency neurological problem, more common in the developing countries due to high incidence of infection, stroke and head injury. The protocol for management of SE is intravenous benzodiazepine, followed by phenytoin, valproate (VPA) and phenobarbitone and if uncontrolled general anesthesia (GA). World Federation of Neurology recommends special guidelines for resource poor countries. Use of GA results in hypotension and respiratory depression needing intensive care management. There is a paucity of intensive care facilities hence the recommended antiepileptic drugs (AEDs) which have inherent toxicity of hypotension and respiratory failure cannot be given safely. Under these situations AEDs such as VPA, levetiracetam and lacosamide may be evaluated in SE because of cardiovascular and respiratory safety profile. In this review, the limitations of existing guidelines in the developing countries have been discussed and a way forward has been suggested.http://www.annalsofian.org/article.asp?issn=0972-2327;year=2014;volume=17;issue=5;spage=27;epage=31;aulast=MisraAnesthetic agentantiepileptic drugrefractory statusstatus epilepticusrespiratory failurehypotension |
| spellingShingle | Usha Kant Misra Jayantee Kalita Sanjeev Kumar Bhoi Practice parameters in management of status epileptics Annals of Indian Academy of Neurology Anesthetic agent antiepileptic drug refractory status status epilepticus respiratory failure hypotension |
| title | Practice parameters in management of status epileptics |
| title_full | Practice parameters in management of status epileptics |
| title_fullStr | Practice parameters in management of status epileptics |
| title_full_unstemmed | Practice parameters in management of status epileptics |
| title_short | Practice parameters in management of status epileptics |
| title_sort | practice parameters in management of status epileptics |
| topic | Anesthetic agent antiepileptic drug refractory status status epilepticus respiratory failure hypotension |
| url | http://www.annalsofian.org/article.asp?issn=0972-2327;year=2014;volume=17;issue=5;spage=27;epage=31;aulast=Misra |
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