Novel strategy of combined interstitial macrophage depletion with intravenous targeted therapy to ameliorate pulmonary fibrosis

Novel strategy of combined interstitial macrophage depletion with intravenous targeted therapy to ameliorate pulmonary fibrosis

Idiopathic pulmonary fibrosis (IPF) is a severe interstitial lung disease with poor prognosis and high mortality rate. In the process of IPF, inflammatory dysregulation of macrophages and massive fibroblast aggregation and proliferation destroy alveoli, which cause pulmonary dysfunction, and ultimat...

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Bibliographic Details
Main Authors: Zhongxian Li, Qiang Zhang, Jiawei Xiang, Mingyuan Zhao, Yuan Meng, Xuhao Hu, Tingting Li, Yifeng Nie, Huizhen Sun, Tun Yan, Zhuo Ao, Dong Han
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Materials Today Bio
Subjects:
Combined strategy
Intervaginal space injection
Macrophage depletion
Pulmonary fibrosis
Targeted therapy
Online Access:http://www.sciencedirect.com/science/article/pii/S2590006423001138

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http://www.sciencedirect.com/science/article/pii/S2590006423001138

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