Novel strategy of combined interstitial macrophage depletion with intravenous targeted therapy to ameliorate pulmonary fibrosis
Idiopathic pulmonary fibrosis (IPF) is a severe interstitial lung disease with poor prognosis and high mortality rate. In the process of IPF, inflammatory dysregulation of macrophages and massive fibroblast aggregation and proliferation destroy alveoli, which cause pulmonary dysfunction, and ultimat...
Main Authors: | Zhongxian Li, Qiang Zhang, Jiawei Xiang, Mingyuan Zhao, Yuan Meng, Xuhao Hu, Tingting Li, Yifeng Nie, Huizhen Sun, Tun Yan, Zhuo Ao, Dong Han |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-06-01
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Series: | Materials Today Bio |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2590006423001138 |
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