The incidence of acute myeloid leukemia in Calgary, Alberta, Canada: a retrospective cohort study
Abstract Background The incidence rate of acute myeloid leukemia (AML) was determined in the Calgary Metropolitan Area, a major Canadian city. Methods Data from all patients diagnosed with AML between January 1, 2011 and December 31, 2015 were retrieved from a single, centralized cancer cytogenetics...
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| Format: | Article |
| Language: | English |
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BMC
2017-08-01
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| Series: | BMC Public Health |
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| Online Access: | http://link.springer.com/article/10.1186/s12889-017-4644-6 |
| _version_ | 1817978957714161664 |
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| author | Andrea Christine Shysh Leonard Tu Nguyen Maggie Guo Marcus Vaska Christopher Naugler Fariborz Rashid-Kolvear |
| author_facet | Andrea Christine Shysh Leonard Tu Nguyen Maggie Guo Marcus Vaska Christopher Naugler Fariborz Rashid-Kolvear |
| author_sort | Andrea Christine Shysh |
| collection | DOAJ |
| description | Abstract Background The incidence rate of acute myeloid leukemia (AML) was determined in the Calgary Metropolitan Area, a major Canadian city. Methods Data from all patients diagnosed with AML between January 1, 2011 and December 31, 2015 were retrieved from a single, centralized cancer cytogenetics laboratory for bone marrow samples, the sole diagnostic facility of its kind in Southern Alberta. Results The calculated incidence rate was 2.79 cases per 100,000 person-years with a median age of 60, slightly lower than previously published data. The age-standardized incidence rate for Canada was 3.46 cases per 100,000 person-years. The higher value is reflective of Calgary’s younger population compared to the rest of Canada. Higher male incidence and greatest incidence occurring at approximately the age of 85 is similar to data from other developed countries. The lower incidence rates and median age of diagnosis, in comparison with that of other high-income nations, may be due to differences in the proportion of aging citizens in the population. Conclusion This is the first published incidence rate of acute myeloid leukemia (AML) in Canada across all age groups. |
| first_indexed | 2024-04-13T22:36:47Z |
| format | Article |
| id | doaj.art-063e232d612746259be3c3c199c9d633 |
| institution | Directory Open Access Journal |
| issn | 1471-2458 |
| language | English |
| last_indexed | 2024-04-13T22:36:47Z |
| publishDate | 2017-08-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Public Health |
| spelling | doaj.art-063e232d612746259be3c3c199c9d6332022-12-22T02:26:45ZengBMCBMC Public Health1471-24582017-08-011811510.1186/s12889-017-4644-6The incidence of acute myeloid leukemia in Calgary, Alberta, Canada: a retrospective cohort studyAndrea Christine Shysh0Leonard Tu Nguyen1Maggie Guo2Marcus Vaska3Christopher Naugler4Fariborz Rashid-Kolvear5Department of Pathology and Laboratory Medicine, Cumming School of Medicine, University of CalgaryDepartment of Pathology and Laboratory Medicine, Cumming School of Medicine, University of CalgaryCalgary Laboratory ServicesKnowledge Resource Service, Alberta Health ServicesDepartment of Pathology and Laboratory Medicine, Cumming School of Medicine, University of CalgaryDepartment of Pathology and Laboratory Medicine, Cumming School of Medicine, University of CalgaryAbstract Background The incidence rate of acute myeloid leukemia (AML) was determined in the Calgary Metropolitan Area, a major Canadian city. Methods Data from all patients diagnosed with AML between January 1, 2011 and December 31, 2015 were retrieved from a single, centralized cancer cytogenetics laboratory for bone marrow samples, the sole diagnostic facility of its kind in Southern Alberta. Results The calculated incidence rate was 2.79 cases per 100,000 person-years with a median age of 60, slightly lower than previously published data. The age-standardized incidence rate for Canada was 3.46 cases per 100,000 person-years. The higher value is reflective of Calgary’s younger population compared to the rest of Canada. Higher male incidence and greatest incidence occurring at approximately the age of 85 is similar to data from other developed countries. The lower incidence rates and median age of diagnosis, in comparison with that of other high-income nations, may be due to differences in the proportion of aging citizens in the population. Conclusion This is the first published incidence rate of acute myeloid leukemia (AML) in Canada across all age groups.http://link.springer.com/article/10.1186/s12889-017-4644-6Acute myeloid leukemiaAcute myelogenous leukemiaCancer epidemiologyHematological neoplasm, incidenceCanada |
| spellingShingle | Andrea Christine Shysh Leonard Tu Nguyen Maggie Guo Marcus Vaska Christopher Naugler Fariborz Rashid-Kolvear The incidence of acute myeloid leukemia in Calgary, Alberta, Canada: a retrospective cohort study BMC Public Health Acute myeloid leukemia Acute myelogenous leukemia Cancer epidemiology Hematological neoplasm, incidence Canada |
| title | The incidence of acute myeloid leukemia in Calgary, Alberta, Canada: a retrospective cohort study |
| title_full | The incidence of acute myeloid leukemia in Calgary, Alberta, Canada: a retrospective cohort study |
| title_fullStr | The incidence of acute myeloid leukemia in Calgary, Alberta, Canada: a retrospective cohort study |
| title_full_unstemmed | The incidence of acute myeloid leukemia in Calgary, Alberta, Canada: a retrospective cohort study |
| title_short | The incidence of acute myeloid leukemia in Calgary, Alberta, Canada: a retrospective cohort study |
| title_sort | incidence of acute myeloid leukemia in calgary alberta canada a retrospective cohort study |
| topic | Acute myeloid leukemia Acute myelogenous leukemia Cancer epidemiology Hematological neoplasm, incidence Canada |
| url | http://link.springer.com/article/10.1186/s12889-017-4644-6 |
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