Factors associated with the incidence of coronary heart disease in the MASHAD cohort study: A six years follow up
Background Coronary heart disease (CHD) is the leading cause of morbidity and mortality globally, and specifically in Iran. Accurate assessments of Coronary heart disease (CHD) incidence is very necessary for public health. In current study we aimed to investigate the incidence of CHD and impor...
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| Format: | Article |
| Language: | English |
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Tehran University of Medical Sciences
2022-07-01
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| Series: | Journal of Biostatistics and Epidemiology |
| Subjects: | |
| Online Access: | https://jbe.tums.ac.ir/index.php/jbe/article/view/700 |
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| author | majid Ghayour-Mobarhan Fatemeh Sadabadi Mohsen Moohebati Alireza Heidari-Bakavoli Sousan Darroudi Shahin Nazarpour Mohammad Sadegh Khorrami Mohebbseraj Zahra Asadi Habibollah Esmaeily Hamideh Ghazizadeh Elham Barati Najmeh malekzadeh Gonabadi Sara Samadi Maryam Tayefi Zahra Izadi mood Mahmoud Reza Azarpazhooh Sahar Heidari- Bakavoli Tara Hoori Ramin Bahramizadeh Sajjadi Gordon Ferns Hamid Heidarian Miri |
| author_facet | majid Ghayour-Mobarhan Fatemeh Sadabadi Mohsen Moohebati Alireza Heidari-Bakavoli Sousan Darroudi Shahin Nazarpour Mohammad Sadegh Khorrami Mohebbseraj Zahra Asadi Habibollah Esmaeily Hamideh Ghazizadeh Elham Barati Najmeh malekzadeh Gonabadi Sara Samadi Maryam Tayefi Zahra Izadi mood Mahmoud Reza Azarpazhooh Sahar Heidari- Bakavoli Tara Hoori Ramin Bahramizadeh Sajjadi Gordon Ferns Hamid Heidarian Miri |
| author_sort | majid Ghayour-Mobarhan |
| collection | DOAJ |
| description | Background
Coronary heart disease (CHD) is the leading cause of morbidity and mortality globally, and specifically in Iran. Accurate assessments of Coronary heart disease (CHD) incidence is very necessary for public health. In current study we aimed to investigate the incidence of CHD and
importance of several classical, modifiable and un-modifiable risk factors for CHD among an urban population in eastern Iran after 6 years of follow-up.
Methods
The population of MASHAD cohort study were followed up for 6 years, every 3 years in two step by phone and who reported symptoms of CVD were asked to attend for a cardiac examination, to estimate the incidence of CHD with 95% confidence interval (95% CI) as well multiple logistic regression analysis was performed to assess the association of several baseline characteristics with incidence of CHD event. Evaluation of goodness-of-fit was done using ROC analysis. CHD cases divided into four different classes which include: stable angina, unstable angina pectoris, myocardial infarction and sudden cardiac death.
Results
In the six years' follow-up of Mashhad study, the incidence rate of all CHD event in men and women in 100,000 people-years with 95% confidence intervals were 1920 (810-3030) and 1160 (730-1590), respectively. The areas under ROC curve (AUC), based on multivariate predictors of CHD outcome, was 0.7825.
Conclusion
Our findings indicated that the incidence rate of coronary heart diseases in MASHAD cohort study increases with age as well as our final model designed, was able to predict approximately 78% of CHD events in Iranian population.
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| first_indexed | 2024-04-13T02:16:36Z |
| format | Article |
| id | doaj.art-063f367cfd684f648729dec34d7b56bd |
| institution | Directory Open Access Journal |
| issn | 2383-4196 2383-420X |
| language | English |
| last_indexed | 2024-04-13T02:16:36Z |
| publishDate | 2022-07-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Journal of Biostatistics and Epidemiology |
| spelling | doaj.art-063f367cfd684f648729dec34d7b56bd2022-12-22T03:07:07ZengTehran University of Medical SciencesJournal of Biostatistics and Epidemiology2383-41962383-420X2022-07-0182Factors associated with the incidence of coronary heart disease in the MASHAD cohort study: A six years follow upmajid Ghayour-Mobarhan0Fatemeh Sadabadi1Mohsen Moohebati2Alireza Heidari-Bakavoli3Sousan Darroudi4Shahin Nazarpour5Mohammad Sadegh Khorrami Mohebbseraj6Zahra Asadi7Habibollah Esmaeily8Hamideh Ghazizadeh9Elham Barati10Najmeh malekzadeh Gonabadi11Sara Samadi12Maryam Tayefi13Zahra Izadi mood14Mahmoud Reza Azarpazhooh15Sahar Heidari- Bakavoli16Tara Hoori17Ramin Bahramizadeh Sajjadi18Gordon Ferns19Hamid Heidarian Miri2010. International UNESCO Center for Health-Related Basic Sciences and Human Nutrition, Department of Nutrition, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.Metabolic syndrome Research center, Mashhad University of Medical Sciences, Mashhad, Iran.Metabolic syndrome Research center, Mashhad University of Medical Sciences, Mashhad, Iran.Metabolic syndrome Research center, Mashhad University of Medical Sciences, Mashhad, Iran.Metabolic syndrome Research center, Mashhad University of Medical Sciences, Mashhad, Iran. Cardiovascular Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.Metabolic syndrome Research center, Mashhad University of Medical Sciences, Mashhad, Iran.Metabolic syndrome Research center, Mashhad University of Medical Sciences, Mashhad, Iran.3. Department of Medical Genetics, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran;Metabolic syndrome Research center, Mashhad University of Medical Sciences, Mashhad, Iran.4. Department of Biostatistics & Epidemiology, School of Health, Management & Social Determinants of Health Research Center, Mashhad University of Medical Sciences, Mashhad, IranMetabolic syndrome Research center, Mashhad University of Medical Sciences, Mashhad, Iran.Metabolic syndrome Research center, Mashhad University of Medical Sciences, Mashhad, Iran.Metabolic syndrome Research center, Mashhad University of Medical Sciences, Mashhad, Iran.Metabolic syndrome Research center, Mashhad University of Medical Sciences, Mashhad, Iran.Metabolic syndrome Research center, Mashhad University of Medical Sciences, Mashhad, Iran.Metabolic syndrome Research center, Mashhad University of Medical Sciences, Mashhad, Iran.Metabolic syndrome Research center, Mashhad University of Medical Sciences, Mashhad, Iran.Metabolic syndrome Research center, Mashhad University of Medical Sciences, Mashhad, Iran.Metabolic syndrome Research center, Mashhad University of Medical Sciences, Mashhad, Iran.Metabolic syndrome Research center, Mashhad University of Medical Sciences, Mashhad, Iran.9. Department of Medical Education, Brighton & Sussex Medical School, Brighton, BN1 9PH, UKDepartment of Biostatistics & Epidemiology, School of Health, Management & Social Determinants of Health Research Center, Mashhad University of Medical Sciences, Mashhad, IranBackground Coronary heart disease (CHD) is the leading cause of morbidity and mortality globally, and specifically in Iran. Accurate assessments of Coronary heart disease (CHD) incidence is very necessary for public health. In current study we aimed to investigate the incidence of CHD and importance of several classical, modifiable and un-modifiable risk factors for CHD among an urban population in eastern Iran after 6 years of follow-up. Methods The population of MASHAD cohort study were followed up for 6 years, every 3 years in two step by phone and who reported symptoms of CVD were asked to attend for a cardiac examination, to estimate the incidence of CHD with 95% confidence interval (95% CI) as well multiple logistic regression analysis was performed to assess the association of several baseline characteristics with incidence of CHD event. Evaluation of goodness-of-fit was done using ROC analysis. CHD cases divided into four different classes which include: stable angina, unstable angina pectoris, myocardial infarction and sudden cardiac death. Results In the six years' follow-up of Mashhad study, the incidence rate of all CHD event in men and women in 100,000 people-years with 95% confidence intervals were 1920 (810-3030) and 1160 (730-1590), respectively. The areas under ROC curve (AUC), based on multivariate predictors of CHD outcome, was 0.7825. Conclusion Our findings indicated that the incidence rate of coronary heart diseases in MASHAD cohort study increases with age as well as our final model designed, was able to predict approximately 78% of CHD events in Iranian population. https://jbe.tums.ac.ir/index.php/jbe/article/view/700MASHAD cohort studyincidencecoronary heart diseasemultivariate predictors |
| spellingShingle | majid Ghayour-Mobarhan Fatemeh Sadabadi Mohsen Moohebati Alireza Heidari-Bakavoli Sousan Darroudi Shahin Nazarpour Mohammad Sadegh Khorrami Mohebbseraj Zahra Asadi Habibollah Esmaeily Hamideh Ghazizadeh Elham Barati Najmeh malekzadeh Gonabadi Sara Samadi Maryam Tayefi Zahra Izadi mood Mahmoud Reza Azarpazhooh Sahar Heidari- Bakavoli Tara Hoori Ramin Bahramizadeh Sajjadi Gordon Ferns Hamid Heidarian Miri Factors associated with the incidence of coronary heart disease in the MASHAD cohort study: A six years follow up Journal of Biostatistics and Epidemiology MASHAD cohort study incidence coronary heart disease multivariate predictors |
| title | Factors associated with the incidence of coronary heart disease in the MASHAD cohort study: A six years follow up |
| title_full | Factors associated with the incidence of coronary heart disease in the MASHAD cohort study: A six years follow up |
| title_fullStr | Factors associated with the incidence of coronary heart disease in the MASHAD cohort study: A six years follow up |
| title_full_unstemmed | Factors associated with the incidence of coronary heart disease in the MASHAD cohort study: A six years follow up |
| title_short | Factors associated with the incidence of coronary heart disease in the MASHAD cohort study: A six years follow up |
| title_sort | factors associated with the incidence of coronary heart disease in the mashad cohort study a six years follow up |
| topic | MASHAD cohort study incidence coronary heart disease multivariate predictors |
| url | https://jbe.tums.ac.ir/index.php/jbe/article/view/700 |
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