A Shigella flexneri 2a synthetic glycan-based vaccine induces a long-lasting immune response in adults
Abstract Shigella is a leading cause of moderate to severe diarrhea worldwide and of diarrhea-associated deaths in children under 5 years of age in low-and middle-income countries. A vaccine against shigellosis is in high demand. SF2a-TT15, a synthetic carbohydrate-based conjugate vaccine candidate...
Main Authors: | Shiri Meron-Sudai, Valeria Asato, Amos Adler, Anya Bialik, Sophy Goren, Ortal Ariel-Cohen, Arava Reizis, Laurence A. Mulard, Armelle Phalipon, Dani Cohen |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-03-01
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Series: | npj Vaccines |
Online Access: | https://doi.org/10.1038/s41541-023-00624-y |
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