Acute Abdomen Due to Uncontrolled Use of Warfarin: Spontaneous Intra-abdominal

Warfarin is an oral anticoagulant, which is commonly used in the treatment and prophylaxis of thromboembolic conditions. Bleeding is the primary adverse effect associated with warfarin. The majority of warfarin-related bleedings are spontaneous minor hemorrhages occurring in the subcutaneous or intr...

Full description

Bibliographic Details
Main Authors: Fatih Dal, Hasan Ökmen, Turgay Erginel, Meltem Küçük Yılmaz, Önder Akkuş, Serkan Sarı
Format: Article
Language:English
Published: Galenos Yayinevi 2017-12-01
Series:Haseki Tıp Bülteni
Subjects:
Online Access:http://www.hasekidergisi.com/archives/archive-detail/article-preview/acute-abdomen-due-to-uncontrolled-use-of-warfarin-/16603
_version_ 1797923136208896000
author Fatih Dal
Hasan Ökmen
Turgay Erginel
Meltem Küçük Yılmaz
Önder Akkuş
Serkan Sarı
author_facet Fatih Dal
Hasan Ökmen
Turgay Erginel
Meltem Küçük Yılmaz
Önder Akkuş
Serkan Sarı
author_sort Fatih Dal
collection DOAJ
description Warfarin is an oral anticoagulant, which is commonly used in the treatment and prophylaxis of thromboembolic conditions. Bleeding is the primary adverse effect associated with warfarin. The majority of warfarin-related bleedings are spontaneous minor hemorrhages occurring in the subcutaneous or intramuscular tissues and can be treated by decreasing the dose of oral anticoagulants. However, although rare, it is possible to encounter spontaneous major bleedings with increased risk of mortality. Conservative approach is the preferred initial therapy for hemodynamically stable patients with major intra-abdominal hemorrhages that we define as the intermediate group patients. Nevertheless, surgery is required for hemodynamically unstable patients with acute abdominal pain in cases of ongoing active hemorrhage, generalized peritonitis, obstruction, acute abdomen, intestinal ischemia, and perforation. In this article, we present a rare case of acute abdomen and spontaneous intra-abdominal hemorrhage resulting from uncontrolled use of warfarin and a new classification requirement.
first_indexed 2024-04-10T14:42:09Z
format Article
id doaj.art-0643f2d73e2946a8aa74af21e48d27d5
institution Directory Open Access Journal
issn 1302-0072
2147-2688
language English
last_indexed 2024-04-10T14:42:09Z
publishDate 2017-12-01
publisher Galenos Yayinevi
record_format Article
series Haseki Tıp Bülteni
spelling doaj.art-0643f2d73e2946a8aa74af21e48d27d52023-02-15T16:08:07ZengGalenos YayineviHaseki Tıp Bülteni1302-00722147-26882017-12-0155431531810.4274/haseki.43534Acute Abdomen Due to Uncontrolled Use of Warfarin: Spontaneous Intra-abdominalFatih Dal0Hasan Ökmen1Turgay Erginel2Meltem Küçük Yılmaz3Önder Akkuş4Serkan Sarı5University of Health Sciences, İstanbul Training and Research Hospital, Clinic of General Surgery, İstanbul, TurkeyUniversity of Health Sciences, İstanbul Training and Research Hospital, Clinic of General Surgery, İstanbul, TurkeyUniversity of Health Sciences, İstanbul Training and Research Hospital, Clinic of General Surgery, İstanbul, TurkeyUniversity of Health Sciences, İstanbul Training and Research Hospital, Clinic of General Surgery, İstanbul, TurkeyUniversity of Health Sciences, İstanbul Training and Research Hospital, Clinic of General Surgery, İstanbul, TurkeyUniversity of Health Sciences, İstanbul Training and Research Hospital, Clinic of General Surgery, İstanbul, TurkeyWarfarin is an oral anticoagulant, which is commonly used in the treatment and prophylaxis of thromboembolic conditions. Bleeding is the primary adverse effect associated with warfarin. The majority of warfarin-related bleedings are spontaneous minor hemorrhages occurring in the subcutaneous or intramuscular tissues and can be treated by decreasing the dose of oral anticoagulants. However, although rare, it is possible to encounter spontaneous major bleedings with increased risk of mortality. Conservative approach is the preferred initial therapy for hemodynamically stable patients with major intra-abdominal hemorrhages that we define as the intermediate group patients. Nevertheless, surgery is required for hemodynamically unstable patients with acute abdominal pain in cases of ongoing active hemorrhage, generalized peritonitis, obstruction, acute abdomen, intestinal ischemia, and perforation. In this article, we present a rare case of acute abdomen and spontaneous intra-abdominal hemorrhage resulting from uncontrolled use of warfarin and a new classification requirement.http://www.hasekidergisi.com/archives/archive-detail/article-preview/acute-abdomen-due-to-uncontrolled-use-of-warfarin-/16603Warfarinacute abdomenbleeding
spellingShingle Fatih Dal
Hasan Ökmen
Turgay Erginel
Meltem Küçük Yılmaz
Önder Akkuş
Serkan Sarı
Acute Abdomen Due to Uncontrolled Use of Warfarin: Spontaneous Intra-abdominal
Haseki Tıp Bülteni
Warfarin
acute abdomen
bleeding
title Acute Abdomen Due to Uncontrolled Use of Warfarin: Spontaneous Intra-abdominal
title_full Acute Abdomen Due to Uncontrolled Use of Warfarin: Spontaneous Intra-abdominal
title_fullStr Acute Abdomen Due to Uncontrolled Use of Warfarin: Spontaneous Intra-abdominal
title_full_unstemmed Acute Abdomen Due to Uncontrolled Use of Warfarin: Spontaneous Intra-abdominal
title_short Acute Abdomen Due to Uncontrolled Use of Warfarin: Spontaneous Intra-abdominal
title_sort acute abdomen due to uncontrolled use of warfarin spontaneous intra abdominal
topic Warfarin
acute abdomen
bleeding
url http://www.hasekidergisi.com/archives/archive-detail/article-preview/acute-abdomen-due-to-uncontrolled-use-of-warfarin-/16603
work_keys_str_mv AT fatihdal acuteabdomenduetouncontrolleduseofwarfarinspontaneousintraabdominal
AT hasanokmen acuteabdomenduetouncontrolleduseofwarfarinspontaneousintraabdominal
AT turgayerginel acuteabdomenduetouncontrolleduseofwarfarinspontaneousintraabdominal
AT meltemkucukyılmaz acuteabdomenduetouncontrolleduseofwarfarinspontaneousintraabdominal
AT onderakkus acuteabdomenduetouncontrolleduseofwarfarinspontaneousintraabdominal
AT serkansarı acuteabdomenduetouncontrolleduseofwarfarinspontaneousintraabdominal