Cognitive impairment after sleep deprivation: The role of precuneus related connectivity on the intra-individual variability changes
Objective: Intra-individual variability (IIV) in cognitive performance is thought to reflect the efficiency with which attentional resources are allocated in different circumstances requiring cognitive control. IIV in cognitive performance is associated with the strength of the negative correlation...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2023-12-01
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| Series: | NeuroImage |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1053811923006134 |
| _version_ | 1797405480959606784 |
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| author | Ziliang Xu Yingjuan Chang Chen Wang Fan Guo Minwen Zheng Peng Fang Yuanqiang Zhu |
| author_facet | Ziliang Xu Yingjuan Chang Chen Wang Fan Guo Minwen Zheng Peng Fang Yuanqiang Zhu |
| author_sort | Ziliang Xu |
| collection | DOAJ |
| description | Objective: Intra-individual variability (IIV) in cognitive performance is thought to reflect the efficiency with which attentional resources are allocated in different circumstances requiring cognitive control. IIV in cognitive performance is associated with the strength of the negative correlation between task-positive network and default mode network (DMN) activity. In this study, we investigated the impact of sleep deprivation (SD) on functional connectivity (FC) between the DMN and psychomotor vigilance task-related network (PVT-RN), and its relationship with IIV in cognitive performance. Methods: Two analyses, network-level independent component analysis (NL-ICA) and region-level (RL)-ICA, were employed to compare the coefficient of variation (CV) of the PVT between normal sleep and SD conditions across 67 healthy participants. Results: After SD, in NL-ICA, the FC between the PVT-RN and DMN was positively correlated with the CV of the PVT, as well as the changes therein, compared with normal sleep. Using a mask derived from the DMN and PVT-RN, the RL-ICA revealed that 12 edges/connections between DMN and PVT independent components were associated with the CV of the PVT, with nine of these connections involving the precuneus. Conclusions: These findings suggest that the precuneus may play a crucial role in the interactions of various brain functions during the PVT, with the connections between the precuneus and frontoparietal and somatosensory networks being significantly altered after SD. Moreover, following SD, weakened negative FC between the precuneus and bilateral inferior parietal lobule may disrupt the balance between cognitive and executive control functions, leading to a decline in cognitive performance. |
| first_indexed | 2024-03-09T03:10:35Z |
| format | Article |
| id | doaj.art-06464ec73e2c4b28866c7560809dce22 |
| institution | Directory Open Access Journal |
| issn | 1095-9572 |
| language | English |
| last_indexed | 2024-03-09T03:10:35Z |
| publishDate | 2023-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | NeuroImage |
| spelling | doaj.art-06464ec73e2c4b28866c7560809dce222023-12-04T05:21:27ZengElsevierNeuroImage1095-95722023-12-01284120462Cognitive impairment after sleep deprivation: The role of precuneus related connectivity on the intra-individual variability changesZiliang Xu0Yingjuan Chang1Chen Wang2Fan Guo3Minwen Zheng4Peng Fang5Yuanqiang Zhu6Department of Radiology, Xijing Hospital, Fourth Military Medical University, 127# Changle West Road, Xi'an 710032, ChinaDepartment of Radiology, Xijing Hospital, Fourth Military Medical University, 127# Changle West Road, Xi'an 710032, ChinaDepartment of Radiology, Xijing Hospital, Fourth Military Medical University, 127# Changle West Road, Xi'an 710032, ChinaDepartment of Radiology, Xijing Hospital, Fourth Military Medical University, 127# Changle West Road, Xi'an 710032, ChinaDepartment of Radiology, Xijing Hospital, Fourth Military Medical University, 127# Changle West Road, Xi'an 710032, ChinaDepartment of Military Medical Psychology, Fourth Military Medical University, 169# Changle West Road, Xi'an 710032, China; Corresponding authors.Department of Radiology, Xijing Hospital, Fourth Military Medical University, 127# Changle West Road, Xi'an 710032, China; Corresponding authors.Objective: Intra-individual variability (IIV) in cognitive performance is thought to reflect the efficiency with which attentional resources are allocated in different circumstances requiring cognitive control. IIV in cognitive performance is associated with the strength of the negative correlation between task-positive network and default mode network (DMN) activity. In this study, we investigated the impact of sleep deprivation (SD) on functional connectivity (FC) between the DMN and psychomotor vigilance task-related network (PVT-RN), and its relationship with IIV in cognitive performance. Methods: Two analyses, network-level independent component analysis (NL-ICA) and region-level (RL)-ICA, were employed to compare the coefficient of variation (CV) of the PVT between normal sleep and SD conditions across 67 healthy participants. Results: After SD, in NL-ICA, the FC between the PVT-RN and DMN was positively correlated with the CV of the PVT, as well as the changes therein, compared with normal sleep. Using a mask derived from the DMN and PVT-RN, the RL-ICA revealed that 12 edges/connections between DMN and PVT independent components were associated with the CV of the PVT, with nine of these connections involving the precuneus. Conclusions: These findings suggest that the precuneus may play a crucial role in the interactions of various brain functions during the PVT, with the connections between the precuneus and frontoparietal and somatosensory networks being significantly altered after SD. Moreover, following SD, weakened negative FC between the precuneus and bilateral inferior parietal lobule may disrupt the balance between cognitive and executive control functions, leading to a decline in cognitive performance.http://www.sciencedirect.com/science/article/pii/S1053811923006134Sleep deprivationIntra-individual variabilityIndependent component analysisFunctional magnetic resonance imagingPsychomotor vigilance task |
| spellingShingle | Ziliang Xu Yingjuan Chang Chen Wang Fan Guo Minwen Zheng Peng Fang Yuanqiang Zhu Cognitive impairment after sleep deprivation: The role of precuneus related connectivity on the intra-individual variability changes NeuroImage Sleep deprivation Intra-individual variability Independent component analysis Functional magnetic resonance imaging Psychomotor vigilance task |
| title | Cognitive impairment after sleep deprivation: The role of precuneus related connectivity on the intra-individual variability changes |
| title_full | Cognitive impairment after sleep deprivation: The role of precuneus related connectivity on the intra-individual variability changes |
| title_fullStr | Cognitive impairment after sleep deprivation: The role of precuneus related connectivity on the intra-individual variability changes |
| title_full_unstemmed | Cognitive impairment after sleep deprivation: The role of precuneus related connectivity on the intra-individual variability changes |
| title_short | Cognitive impairment after sleep deprivation: The role of precuneus related connectivity on the intra-individual variability changes |
| title_sort | cognitive impairment after sleep deprivation the role of precuneus related connectivity on the intra individual variability changes |
| topic | Sleep deprivation Intra-individual variability Independent component analysis Functional magnetic resonance imaging Psychomotor vigilance task |
| url | http://www.sciencedirect.com/science/article/pii/S1053811923006134 |
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