A Temporal–Spatial Atlas of Peripheral Nerve Evoked Cortex Potential in Rat: A Novel Testbed to Explore the Responding Patterns of the Brain to Peripheral Nerves
Observing the dynamic progress of the brain in response to peripheral nerve stimulation as a whole is the basis for a deeper understanding of overall brain function; however, it remains a great challenge. In this work, a novel mini-invasive orthogonal recording method is developed to observe the ove...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2022-07-01
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| Series: | Engineering |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2095809921002344 |
| _version_ | 1817999632255418368 |
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| author | Xiaofeng Yin Jiuxu Deng Bo Chen Bo Jin Xinyi Gu Zhidan Qi Kunpeng Leng Baoguo Jiang |
| author_facet | Xiaofeng Yin Jiuxu Deng Bo Chen Bo Jin Xinyi Gu Zhidan Qi Kunpeng Leng Baoguo Jiang |
| author_sort | Xiaofeng Yin |
| collection | DOAJ |
| description | Observing the dynamic progress of the brain in response to peripheral nerve stimulation as a whole is the basis for a deeper understanding of overall brain function; however, it remains a great challenge. In this work, a novel mini-invasive orthogonal recording method is developed to observe the overall evoked cortex potential (ECP) in rat brain. A typical ECP atlas with recognizable waveforms in the rat cortex corresponding to the median, ulnar, and radial nerve trunks and subdivided branches is acquired. Reproducible exciting temporal–spatial progress in the rat brain is obtained and visualized for the first time. Changes in the ECPs and exciting sequences in the cortex four months after median nerve transection are also observed. The results suggest that the brain’s response to peripheral stimulation has precise and reproducible temporal–spatial properties. This resource can serve as a testbed to explore the overall functional interaction and dynamic remodeling mechanisms between the peripheral and central nervous systems over time. |
| first_indexed | 2024-04-14T03:11:06Z |
| format | Article |
| id | doaj.art-064764c1d8994402a41fd18433de19a6 |
| institution | Directory Open Access Journal |
| issn | 2095-8099 |
| language | English |
| last_indexed | 2024-04-14T03:11:06Z |
| publishDate | 2022-07-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Engineering |
| spelling | doaj.art-064764c1d8994402a41fd18433de19a62022-12-22T02:15:35ZengElsevierEngineering2095-80992022-07-0114147155A Temporal–Spatial Atlas of Peripheral Nerve Evoked Cortex Potential in Rat: A Novel Testbed to Explore the Responding Patterns of the Brain to Peripheral NervesXiaofeng Yin0Jiuxu Deng1Bo Chen2Bo Jin3Xinyi Gu4Zhidan Qi5Kunpeng Leng6Baoguo Jiang7Corresponding authors.; Department of Trauma and Orthopedics, Peking University People’s Hospital, Beijing 100044, ChinaDepartment of Trauma and Orthopedics, Peking University People’s Hospital, Beijing 100044, ChinaDepartment of Trauma and Orthopedics, Peking University People’s Hospital, Beijing 100044, ChinaDepartment of Trauma and Orthopedics, Peking University People’s Hospital, Beijing 100044, ChinaDepartment of Trauma and Orthopedics, Peking University People’s Hospital, Beijing 100044, ChinaDepartment of Trauma and Orthopedics, Peking University People’s Hospital, Beijing 100044, ChinaDepartment of Trauma and Orthopedics, Peking University People’s Hospital, Beijing 100044, ChinaCorresponding authors.; Department of Trauma and Orthopedics, Peking University People’s Hospital, Beijing 100044, ChinaObserving the dynamic progress of the brain in response to peripheral nerve stimulation as a whole is the basis for a deeper understanding of overall brain function; however, it remains a great challenge. In this work, a novel mini-invasive orthogonal recording method is developed to observe the overall evoked cortex potential (ECP) in rat brain. A typical ECP atlas with recognizable waveforms in the rat cortex corresponding to the median, ulnar, and radial nerve trunks and subdivided branches is acquired. Reproducible exciting temporal–spatial progress in the rat brain is obtained and visualized for the first time. Changes in the ECPs and exciting sequences in the cortex four months after median nerve transection are also observed. The results suggest that the brain’s response to peripheral stimulation has precise and reproducible temporal–spatial properties. This resource can serve as a testbed to explore the overall functional interaction and dynamic remodeling mechanisms between the peripheral and central nervous systems over time.http://www.sciencedirect.com/science/article/pii/S2095809921002344Peripheral nerveBrainEvoked cortex potentialTemporal–spatialAtlas |
| spellingShingle | Xiaofeng Yin Jiuxu Deng Bo Chen Bo Jin Xinyi Gu Zhidan Qi Kunpeng Leng Baoguo Jiang A Temporal–Spatial Atlas of Peripheral Nerve Evoked Cortex Potential in Rat: A Novel Testbed to Explore the Responding Patterns of the Brain to Peripheral Nerves Engineering Peripheral nerve Brain Evoked cortex potential Temporal–spatial Atlas |
| title | A Temporal–Spatial Atlas of Peripheral Nerve Evoked Cortex Potential in Rat: A Novel Testbed to Explore the Responding Patterns of the Brain to Peripheral Nerves |
| title_full | A Temporal–Spatial Atlas of Peripheral Nerve Evoked Cortex Potential in Rat: A Novel Testbed to Explore the Responding Patterns of the Brain to Peripheral Nerves |
| title_fullStr | A Temporal–Spatial Atlas of Peripheral Nerve Evoked Cortex Potential in Rat: A Novel Testbed to Explore the Responding Patterns of the Brain to Peripheral Nerves |
| title_full_unstemmed | A Temporal–Spatial Atlas of Peripheral Nerve Evoked Cortex Potential in Rat: A Novel Testbed to Explore the Responding Patterns of the Brain to Peripheral Nerves |
| title_short | A Temporal–Spatial Atlas of Peripheral Nerve Evoked Cortex Potential in Rat: A Novel Testbed to Explore the Responding Patterns of the Brain to Peripheral Nerves |
| title_sort | temporal spatial atlas of peripheral nerve evoked cortex potential in rat a novel testbed to explore the responding patterns of the brain to peripheral nerves |
| topic | Peripheral nerve Brain Evoked cortex potential Temporal–spatial Atlas |
| url | http://www.sciencedirect.com/science/article/pii/S2095809921002344 |
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