The relationship between first trimester screening test and abruptio placentae

Objective: We compared the first-trimester screening test results and perinatal results of pregnant women to determine the diagnosis of abruptio placentae, one of the essential causes of maternal and fetal mortality and morbidity. Methods: Between 2019 and 2021, 20 pregnant women diagnosed...

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Main Authors: Begüm Kurt, İrem Alyazıcı Küçükyıldız
Format: Article
Language:English
Published: Perinatal Medicine Foundation 2022-04-01
Series:Perinatal Journal
Online Access:https://perinataljournal.com/Archive/Article/20220301011
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author Begüm Kurt
İrem Alyazıcı Küçükyıldız
author_facet Begüm Kurt
İrem Alyazıcı Küçükyıldız
author_sort Begüm Kurt
collection DOAJ
description Objective: We compared the first-trimester screening test results and perinatal results of pregnant women to determine the diagnosis of abruptio placentae, one of the essential causes of maternal and fetal mortality and morbidity. Methods: Between 2019 and 2021, 20 pregnant women diagnosed with abruptio placentae in our hospital and 30 pregnant women who did not develop clinical abruptio placentae during their pregnancy in the same period were included in our study. The relationship between the first-trimester screening test results and the perinatal outcomes of the patients was investigated. Results: No significant differences were found in maternal age, gravida and parity. Significant difference was found in gestational age at birth, being 33±5.1 weeks in the study group and 38.6±1.48 weeks in the control group. No statistical differences were found at PAPP-A or at b-hCG between the groups (p=0.219 and p=0.898, respectively). Nevertheless, a trend of a lower PAPP-A at the study group was noticed (1.03±0.54 MoM vs. 1.28±0.66 MoM). Significant differences were found at fetal birth weight, 1-minute Apgar score and 5-minute Apgar score. When looking at risk factors, no differences between the groups were found at smoking, multiple pregnancy, myoma uteri or diabetes, but preeclampsia and threatened preterm labor were more common at the study group. Conclusion: When we compared the first-trimester serum biomarkers to predict abruptio placentae, we could not find any significant difference between the two groups. To reach a definite conclusion on this issue, more studies with increasing the number of patients are needed.
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spelling doaj.art-06479bb4334c469d851b881109df35892023-02-15T16:07:32ZengPerinatal Medicine FoundationPerinatal Journal1305-31242022-04-01301515610.2399/prn.22.0301011The relationship between first trimester screening test and abruptio placentaeBegüm Kurthttps://orcid.org/0000-0002-7166-3130İrem Alyazıcı Küçükyıldızhttps://orcid.org/0000-0002-6604-0713 Objective: We compared the first-trimester screening test results and perinatal results of pregnant women to determine the diagnosis of abruptio placentae, one of the essential causes of maternal and fetal mortality and morbidity. Methods: Between 2019 and 2021, 20 pregnant women diagnosed with abruptio placentae in our hospital and 30 pregnant women who did not develop clinical abruptio placentae during their pregnancy in the same period were included in our study. The relationship between the first-trimester screening test results and the perinatal outcomes of the patients was investigated. Results: No significant differences were found in maternal age, gravida and parity. Significant difference was found in gestational age at birth, being 33±5.1 weeks in the study group and 38.6±1.48 weeks in the control group. No statistical differences were found at PAPP-A or at b-hCG between the groups (p=0.219 and p=0.898, respectively). Nevertheless, a trend of a lower PAPP-A at the study group was noticed (1.03±0.54 MoM vs. 1.28±0.66 MoM). Significant differences were found at fetal birth weight, 1-minute Apgar score and 5-minute Apgar score. When looking at risk factors, no differences between the groups were found at smoking, multiple pregnancy, myoma uteri or diabetes, but preeclampsia and threatened preterm labor were more common at the study group. Conclusion: When we compared the first-trimester serum biomarkers to predict abruptio placentae, we could not find any significant difference between the two groups. To reach a definite conclusion on this issue, more studies with increasing the number of patients are needed.https://perinataljournal.com/Archive/Article/20220301011
spellingShingle Begüm Kurt
İrem Alyazıcı Küçükyıldız
The relationship between first trimester screening test and abruptio placentae
Perinatal Journal
title The relationship between first trimester screening test and abruptio placentae
title_full The relationship between first trimester screening test and abruptio placentae
title_fullStr The relationship between first trimester screening test and abruptio placentae
title_full_unstemmed The relationship between first trimester screening test and abruptio placentae
title_short The relationship between first trimester screening test and abruptio placentae
title_sort relationship between first trimester screening test and abruptio placentae
url https://perinataljournal.com/Archive/Article/20220301011
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