Association between Plasma Omega-3 and Handgrip Strength According to Glycohemoglobin Levels in Older Adults: Results from NHANES 2011–2012
Background: Low muscle strength is a predictor of mortality in older adults. Although the evidence concerning hyperglycemia is limited, evidence shows that omega-3 (ω-3) intake may be positively associated with muscle strength. However, the association between plasma ω-3 and muscle strength in older...
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| Format: | Article |
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MDPI AG
2022-09-01
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| Series: | Nutrients |
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| Online Access: | https://www.mdpi.com/2072-6643/14/19/4060 |
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| author | Raíssa A. B. Batista Flávia M. S. de Branco Rafaela Nehme Erick P. de Oliveira Geórgia das G. Pena |
| author_facet | Raíssa A. B. Batista Flávia M. S. de Branco Rafaela Nehme Erick P. de Oliveira Geórgia das G. Pena |
| author_sort | Raíssa A. B. Batista |
| collection | DOAJ |
| description | Background: Low muscle strength is a predictor of mortality in older adults. Although the evidence concerning hyperglycemia is limited, evidence shows that omega-3 (ω-3) intake may be positively associated with muscle strength. However, the association between plasma ω-3 and muscle strength in older adults according to glycohemoglobin (HbA1c) levels has not yet been investigated. Objective: To evaluate whether plasma ω-3 levels are associated with handgrip strength in individuals over 50 years according to HbA1c levels. Methods: This cross-sectional study included 950 older adults (50–85 years) from NHANES 2011–2012. Linear regression analysis was performed to evaluate the association between plasma ω-3 and handgrip strength in individuals with elevated (≥5.7%) or normal HbA1c levels after adjustments for confounders. Results: Total plasma ω-3, docosahexaenoic acid, eicosapentaenoic acid and alpha-linolenic acid were not associated with handgrip strength in older adults regardless of HbA1c levels. Conclusion: Plasma ω-3 levels are not associated with handgrip strength in individuals over 50 years old independent of HbA1c levels. |
| first_indexed | 2024-03-09T21:19:26Z |
| format | Article |
| id | doaj.art-0648b7dda7474c7d95934d8dff6c5c4a |
| institution | Directory Open Access Journal |
| issn | 2072-6643 |
| language | English |
| last_indexed | 2024-03-09T21:19:26Z |
| publishDate | 2022-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nutrients |
| spelling | doaj.art-0648b7dda7474c7d95934d8dff6c5c4a2023-11-23T21:24:57ZengMDPI AGNutrients2072-66432022-09-011419406010.3390/nu14194060Association between Plasma Omega-3 and Handgrip Strength According to Glycohemoglobin Levels in Older Adults: Results from NHANES 2011–2012Raíssa A. B. Batista0Flávia M. S. de Branco1Rafaela Nehme2Erick P. de Oliveira3Geórgia das G. Pena4Graduate Program in Health Sciences, School of Medicine, Federal University of Uberlandia (UFU), Uberlandia 38402-018, Minas Gerais, BrazilLaboratory of Nutrition, Exercise and Health (LaNES), School of Medicine, Federal University of Uberlandia (UFU), Uberlandia 38402-018, Minas Gerais, BrazilLaboratory of Nutrition, Exercise and Health (LaNES), School of Medicine, Federal University of Uberlandia (UFU), Uberlandia 38402-018, Minas Gerais, BrazilLaboratory of Nutrition, Exercise and Health (LaNES), School of Medicine, Federal University of Uberlandia (UFU), Uberlandia 38402-018, Minas Gerais, BrazilGraduate Program in Health Sciences, School of Medicine, Federal University of Uberlandia (UFU), Uberlandia 38402-018, Minas Gerais, BrazilBackground: Low muscle strength is a predictor of mortality in older adults. Although the evidence concerning hyperglycemia is limited, evidence shows that omega-3 (ω-3) intake may be positively associated with muscle strength. However, the association between plasma ω-3 and muscle strength in older adults according to glycohemoglobin (HbA1c) levels has not yet been investigated. Objective: To evaluate whether plasma ω-3 levels are associated with handgrip strength in individuals over 50 years according to HbA1c levels. Methods: This cross-sectional study included 950 older adults (50–85 years) from NHANES 2011–2012. Linear regression analysis was performed to evaluate the association between plasma ω-3 and handgrip strength in individuals with elevated (≥5.7%) or normal HbA1c levels after adjustments for confounders. Results: Total plasma ω-3, docosahexaenoic acid, eicosapentaenoic acid and alpha-linolenic acid were not associated with handgrip strength in older adults regardless of HbA1c levels. Conclusion: Plasma ω-3 levels are not associated with handgrip strength in individuals over 50 years old independent of HbA1c levels.https://www.mdpi.com/2072-6643/14/19/4060oxidative stressomega-3older adultsHbA1cimpaired glucose tolerance |
| spellingShingle | Raíssa A. B. Batista Flávia M. S. de Branco Rafaela Nehme Erick P. de Oliveira Geórgia das G. Pena Association between Plasma Omega-3 and Handgrip Strength According to Glycohemoglobin Levels in Older Adults: Results from NHANES 2011–2012 Nutrients oxidative stress omega-3 older adults HbA1c impaired glucose tolerance |
| title | Association between Plasma Omega-3 and Handgrip Strength According to Glycohemoglobin Levels in Older Adults: Results from NHANES 2011–2012 |
| title_full | Association between Plasma Omega-3 and Handgrip Strength According to Glycohemoglobin Levels in Older Adults: Results from NHANES 2011–2012 |
| title_fullStr | Association between Plasma Omega-3 and Handgrip Strength According to Glycohemoglobin Levels in Older Adults: Results from NHANES 2011–2012 |
| title_full_unstemmed | Association between Plasma Omega-3 and Handgrip Strength According to Glycohemoglobin Levels in Older Adults: Results from NHANES 2011–2012 |
| title_short | Association between Plasma Omega-3 and Handgrip Strength According to Glycohemoglobin Levels in Older Adults: Results from NHANES 2011–2012 |
| title_sort | association between plasma omega 3 and handgrip strength according to glycohemoglobin levels in older adults results from nhanes 2011 2012 |
| topic | oxidative stress omega-3 older adults HbA1c impaired glucose tolerance |
| url | https://www.mdpi.com/2072-6643/14/19/4060 |
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