Gastrodin Ameliorates Motor Learning Deficits Through Preserving Cerebellar Long-Term Depression Pathways in Diabetic Rats

Gastrodin Ameliorates Motor Learning Deficits Through Preserving Cerebellar Long-Term Depression Pathways in Diabetic Rats

Cognitive dysfunction is a very severe consequence of diabetes, but the underlying causes are still unclear. Recently, the cerebellum was reported to play an important role in learning and memory. Since long-term depression (LTD) is a primary cellular mechanism for cerebellar motor learning, we aime...

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Bibliographic Details
Main Authors: Cheng-Kun Deng, Zhi-Hao Mu, Yi-He Miao, Yi-Dan Liu, Lei Zhou, Yong-Jie Huang, Fan Zhang, Yao-Yi Wang, Zhi-Hong Yang, Zhong-Yi Qian, Xie Wang, Jia-Zhi Guo, Mei-Yan Zhang, Xin-Yu Liao, Qi Wan, Di Lu, Ying-Ying Zou
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Neuroscience
Subjects:
diabetes
cerebellum
Purkinje cells
LTD
gastrodin
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2019.01239/full

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