Association of bullous pemphigoid with malignancy: A myth or reality?

Bullous pemphigoid (BP) is an autoimmune sub-epidermal blistering disorder of the skin. The association of BP with internal malignancy has always been a matter of debate with no consensus reached despite many published case reports and clinical trials. However, we report a hitherto unreported associ...

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Main Authors: Joycelin Fernandes, Prachi Barad, Pankaj Shukla
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2014-01-01
Series:Indian Journal of Dermatology
Subjects:
Online Access:http://www.e-ijd.org/article.asp?issn=0019-5154;year=2014;volume=59;issue=4;spage=390;epage=393;aulast=Fernandes
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author Joycelin Fernandes
Prachi Barad
Pankaj Shukla
author_facet Joycelin Fernandes
Prachi Barad
Pankaj Shukla
author_sort Joycelin Fernandes
collection DOAJ
description Bullous pemphigoid (BP) is an autoimmune sub-epidermal blistering disorder of the skin. The association of BP with internal malignancy has always been a matter of debate with no consensus reached despite many published case reports and clinical trials. However, we report a hitherto unreported association of BP with squamous cell carcinoma of the tongue, wherein the patient had a recalcitrant downhill course despite adequate treatment measures with control of skin lesions being achieved only following excision of the tumor, and relapse coinciding with detection of metastasis. Hence, given the clinical behavior, it is reasonable to speculate that the association of malignancy was more than co-incidental.
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spelling doaj.art-064de3868f46448abcd2850c4e8c8cd52022-12-21T19:37:24ZengWolters Kluwer Medknow PublicationsIndian Journal of Dermatology0019-51541998-36112014-01-0159439039310.4103/0019-5154.135493Association of bullous pemphigoid with malignancy: A myth or reality?Joycelin FernandesPrachi BaradPankaj ShuklaBullous pemphigoid (BP) is an autoimmune sub-epidermal blistering disorder of the skin. The association of BP with internal malignancy has always been a matter of debate with no consensus reached despite many published case reports and clinical trials. However, we report a hitherto unreported association of BP with squamous cell carcinoma of the tongue, wherein the patient had a recalcitrant downhill course despite adequate treatment measures with control of skin lesions being achieved only following excision of the tumor, and relapse coinciding with detection of metastasis. Hence, given the clinical behavior, it is reasonable to speculate that the association of malignancy was more than co-incidental.http://www.e-ijd.org/article.asp?issn=0019-5154;year=2014;volume=59;issue=4;spage=390;epage=393;aulast=FernandesBullous pemphigoidsquamous cell carcinomaassociation
spellingShingle Joycelin Fernandes
Prachi Barad
Pankaj Shukla
Association of bullous pemphigoid with malignancy: A myth or reality?
Indian Journal of Dermatology
Bullous pemphigoid
squamous cell carcinoma
association
title Association of bullous pemphigoid with malignancy: A myth or reality?
title_full Association of bullous pemphigoid with malignancy: A myth or reality?
title_fullStr Association of bullous pemphigoid with malignancy: A myth or reality?
title_full_unstemmed Association of bullous pemphigoid with malignancy: A myth or reality?
title_short Association of bullous pemphigoid with malignancy: A myth or reality?
title_sort association of bullous pemphigoid with malignancy a myth or reality
topic Bullous pemphigoid
squamous cell carcinoma
association
url http://www.e-ijd.org/article.asp?issn=0019-5154;year=2014;volume=59;issue=4;spage=390;epage=393;aulast=Fernandes
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AT pankajshukla associationofbullouspemphigoidwithmalignancyamythorreality