Rpd3/CoRest-mediated activity-dependent transcription regulates the flexibility in memory updating in Drosophila

The flexibility of memory updating may be determined in the initial memory consolidation process. Here, the authors show the proteomic changes of the transcriptional repressor complexes required for initial memory consolidation and influencing the flexibility of future memory updating.

Bibliographic Details
Main Authors: Mai Takakura, Reiko Nakagawa, Takeshi Ota, Yoko Kimura, Man Yung NG, Abdalla G. Alia, Hiroyuki Okuno, Yukinori Hirano
Format: Article
Language:English
Published: Nature Portfolio 2021-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-20898-x
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author Mai Takakura
Reiko Nakagawa
Takeshi Ota
Yoko Kimura
Man Yung NG
Abdalla G. Alia
Hiroyuki Okuno
Yukinori Hirano
author_facet Mai Takakura
Reiko Nakagawa
Takeshi Ota
Yoko Kimura
Man Yung NG
Abdalla G. Alia
Hiroyuki Okuno
Yukinori Hirano
author_sort Mai Takakura
collection DOAJ
description The flexibility of memory updating may be determined in the initial memory consolidation process. Here, the authors show the proteomic changes of the transcriptional repressor complexes required for initial memory consolidation and influencing the flexibility of future memory updating.
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spelling doaj.art-064fae2728d2455388b7498193e9cf402022-12-21T22:58:13ZengNature PortfolioNature Communications2041-17232021-01-0112111510.1038/s41467-021-20898-xRpd3/CoRest-mediated activity-dependent transcription regulates the flexibility in memory updating in DrosophilaMai Takakura0Reiko Nakagawa1Takeshi Ota2Yoko Kimura3Man Yung NG4Abdalla G. Alia5Hiroyuki Okuno6Yukinori Hirano7Hakubi Center, Kyoto University Graduate School of MedicineLaboratory for Phyloinformatics, RIKEN Center for Biosystems Dynamics ResearchShionogi & Co., Ltd, Laboratory for Innovative Therapy Research, Drug Discovery Technologies 1, Shionogi Pharmaceutical Research CenterHakubi Center, Kyoto University Graduate School of MedicineDivision of Life Science, The Hong Kong University of Science and TechnologyDivision of Life Science, The Hong Kong University of Science and TechnologyDepartment of Biochemistry and Molecular Biology, Graduate School of Medical and Dental Sciences, Kagoshima UniversityHakubi Center, Kyoto University Graduate School of MedicineThe flexibility of memory updating may be determined in the initial memory consolidation process. Here, the authors show the proteomic changes of the transcriptional repressor complexes required for initial memory consolidation and influencing the flexibility of future memory updating.https://doi.org/10.1038/s41467-021-20898-x
spellingShingle Mai Takakura
Reiko Nakagawa
Takeshi Ota
Yoko Kimura
Man Yung NG
Abdalla G. Alia
Hiroyuki Okuno
Yukinori Hirano
Rpd3/CoRest-mediated activity-dependent transcription regulates the flexibility in memory updating in Drosophila
Nature Communications
title Rpd3/CoRest-mediated activity-dependent transcription regulates the flexibility in memory updating in Drosophila
title_full Rpd3/CoRest-mediated activity-dependent transcription regulates the flexibility in memory updating in Drosophila
title_fullStr Rpd3/CoRest-mediated activity-dependent transcription regulates the flexibility in memory updating in Drosophila
title_full_unstemmed Rpd3/CoRest-mediated activity-dependent transcription regulates the flexibility in memory updating in Drosophila
title_short Rpd3/CoRest-mediated activity-dependent transcription regulates the flexibility in memory updating in Drosophila
title_sort rpd3 corest mediated activity dependent transcription regulates the flexibility in memory updating in drosophila
url https://doi.org/10.1038/s41467-021-20898-x
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