Rpd3/CoRest-mediated activity-dependent transcription regulates the flexibility in memory updating in Drosophila
The flexibility of memory updating may be determined in the initial memory consolidation process. Here, the authors show the proteomic changes of the transcriptional repressor complexes required for initial memory consolidation and influencing the flexibility of future memory updating.
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
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Nature Portfolio
2021-01-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-021-20898-x |
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author | Mai Takakura Reiko Nakagawa Takeshi Ota Yoko Kimura Man Yung NG Abdalla G. Alia Hiroyuki Okuno Yukinori Hirano |
author_facet | Mai Takakura Reiko Nakagawa Takeshi Ota Yoko Kimura Man Yung NG Abdalla G. Alia Hiroyuki Okuno Yukinori Hirano |
author_sort | Mai Takakura |
collection | DOAJ |
description | The flexibility of memory updating may be determined in the initial memory consolidation process. Here, the authors show the proteomic changes of the transcriptional repressor complexes required for initial memory consolidation and influencing the flexibility of future memory updating. |
first_indexed | 2024-12-14T14:14:15Z |
format | Article |
id | doaj.art-064fae2728d2455388b7498193e9cf40 |
institution | Directory Open Access Journal |
issn | 2041-1723 |
language | English |
last_indexed | 2024-12-14T14:14:15Z |
publishDate | 2021-01-01 |
publisher | Nature Portfolio |
record_format | Article |
series | Nature Communications |
spelling | doaj.art-064fae2728d2455388b7498193e9cf402022-12-21T22:58:13ZengNature PortfolioNature Communications2041-17232021-01-0112111510.1038/s41467-021-20898-xRpd3/CoRest-mediated activity-dependent transcription regulates the flexibility in memory updating in DrosophilaMai Takakura0Reiko Nakagawa1Takeshi Ota2Yoko Kimura3Man Yung NG4Abdalla G. Alia5Hiroyuki Okuno6Yukinori Hirano7Hakubi Center, Kyoto University Graduate School of MedicineLaboratory for Phyloinformatics, RIKEN Center for Biosystems Dynamics ResearchShionogi & Co., Ltd, Laboratory for Innovative Therapy Research, Drug Discovery Technologies 1, Shionogi Pharmaceutical Research CenterHakubi Center, Kyoto University Graduate School of MedicineDivision of Life Science, The Hong Kong University of Science and TechnologyDivision of Life Science, The Hong Kong University of Science and TechnologyDepartment of Biochemistry and Molecular Biology, Graduate School of Medical and Dental Sciences, Kagoshima UniversityHakubi Center, Kyoto University Graduate School of MedicineThe flexibility of memory updating may be determined in the initial memory consolidation process. Here, the authors show the proteomic changes of the transcriptional repressor complexes required for initial memory consolidation and influencing the flexibility of future memory updating.https://doi.org/10.1038/s41467-021-20898-x |
spellingShingle | Mai Takakura Reiko Nakagawa Takeshi Ota Yoko Kimura Man Yung NG Abdalla G. Alia Hiroyuki Okuno Yukinori Hirano Rpd3/CoRest-mediated activity-dependent transcription regulates the flexibility in memory updating in Drosophila Nature Communications |
title | Rpd3/CoRest-mediated activity-dependent transcription regulates the flexibility in memory updating in Drosophila |
title_full | Rpd3/CoRest-mediated activity-dependent transcription regulates the flexibility in memory updating in Drosophila |
title_fullStr | Rpd3/CoRest-mediated activity-dependent transcription regulates the flexibility in memory updating in Drosophila |
title_full_unstemmed | Rpd3/CoRest-mediated activity-dependent transcription regulates the flexibility in memory updating in Drosophila |
title_short | Rpd3/CoRest-mediated activity-dependent transcription regulates the flexibility in memory updating in Drosophila |
title_sort | rpd3 corest mediated activity dependent transcription regulates the flexibility in memory updating in drosophila |
url | https://doi.org/10.1038/s41467-021-20898-x |
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