Protocol for inferring epithelial-to-mesenchymal transition trajectories from single-cell RNA sequencing data using R

Protocol for inferring epithelial-to-mesenchymal transition trajectories from single-cell RNA sequencing data using R

Summary: The epithelial-to-mesenchymal transition (EMT) provides crucial insights into the metastatic process and possesses prognostic value within the cancer context. Here, we present COMET, an R package for inferring EMT trajectories and inter-state transition rates from single-cell RNA sequencing...

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Bibliographic Details
Main Authors: Annice Najafi, Mohit Kumar Jolly, Jason T. George
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:STAR Protocols
Subjects:
Bioinformatics
Cancer
RNA-seq
Online Access:http://www.sciencedirect.com/science/article/pii/S2666166723007864

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