Utility of MPT64 antigen detection for rapid confirmation of mycobacterium tuberculosis complex
Background: Rapid differentiation of the Mycobacterium tuberculosis complex (MTBC) and mycobacteria other than tuberculosis (MOTT) is crucial to facilitate early and effective treatment of the patients. Clinical presentation of MTBC and MOTT is not always very clear and routine conventional methods...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2015-01-01
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| Series: | Journal of Global Infectious Diseases |
| Subjects: | |
| Online Access: | http://www.jgid.org/article.asp?issn=0974-777X;year=2015;volume=7;issue=2;spage=66;epage=69;aulast=Arora |
| _version_ | 1828770650474414080 |
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| author | Jyoti Arora Gavish Kumar Ajoy Kumar Verma Manpreet Bhalla Rohit Sarin Vithal Prasad Myneedu |
| author_facet | Jyoti Arora Gavish Kumar Ajoy Kumar Verma Manpreet Bhalla Rohit Sarin Vithal Prasad Myneedu |
| author_sort | Jyoti Arora |
| collection | DOAJ |
| description | Background: Rapid differentiation of the Mycobacterium tuberculosis complex (MTBC) and mycobacteria other than tuberculosis (MOTT) is crucial to facilitate early and effective treatment of the patients. Clinical presentation of MTBC and MOTT is not always very clear and routine conventional methods are time consuming. Materials and Methods: In the present study, the MPT64 protein detection-based immunochomatographic test (SD Bioline Kit, Standard Diagnostics, Inc., Korea) was compared with the conventional biochemical method. Results: The sensitivity, specificity, positive predictive, and negative predictive values of the SD AgMPT64 kit were found to be 100, 96.4, 98.72, and 100%, respectively. Conclusions: Our results have demonstrated that the SD bioline kit is a rapid, reliable method and it can be used in the Revised National Tuberculosis Control Program (RNTCP) of India, for the appropriate management of tuberculosis. |
| first_indexed | 2024-12-11T14:10:59Z |
| format | Article |
| id | doaj.art-0652a956c3a24d3da29408a98a820872 |
| institution | Directory Open Access Journal |
| issn | 0974-777X |
| language | English |
| last_indexed | 2024-12-11T14:10:59Z |
| publishDate | 2015-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Global Infectious Diseases |
| spelling | doaj.art-0652a956c3a24d3da29408a98a8208722022-12-22T01:03:25ZengWolters Kluwer Medknow PublicationsJournal of Global Infectious Diseases0974-777X2015-01-0172666910.4103/0974-777X.154443Utility of MPT64 antigen detection for rapid confirmation of mycobacterium tuberculosis complexJyoti AroraGavish KumarAjoy Kumar VermaManpreet BhallaRohit SarinVithal Prasad MyneeduBackground: Rapid differentiation of the Mycobacterium tuberculosis complex (MTBC) and mycobacteria other than tuberculosis (MOTT) is crucial to facilitate early and effective treatment of the patients. Clinical presentation of MTBC and MOTT is not always very clear and routine conventional methods are time consuming. Materials and Methods: In the present study, the MPT64 protein detection-based immunochomatographic test (SD Bioline Kit, Standard Diagnostics, Inc., Korea) was compared with the conventional biochemical method. Results: The sensitivity, specificity, positive predictive, and negative predictive values of the SD AgMPT64 kit were found to be 100, 96.4, 98.72, and 100%, respectively. Conclusions: Our results have demonstrated that the SD bioline kit is a rapid, reliable method and it can be used in the Revised National Tuberculosis Control Program (RNTCP) of India, for the appropriate management of tuberculosis.http://www.jgid.org/article.asp?issn=0974-777X;year=2015;volume=7;issue=2;spage=66;epage=69;aulast=AroraBiochemical identificationMPT64 antigenM. tuberculosis complex |
| spellingShingle | Jyoti Arora Gavish Kumar Ajoy Kumar Verma Manpreet Bhalla Rohit Sarin Vithal Prasad Myneedu Utility of MPT64 antigen detection for rapid confirmation of mycobacterium tuberculosis complex Journal of Global Infectious Diseases Biochemical identification MPT64 antigen M. tuberculosis complex |
| title | Utility of MPT64 antigen detection for rapid confirmation of mycobacterium tuberculosis complex |
| title_full | Utility of MPT64 antigen detection for rapid confirmation of mycobacterium tuberculosis complex |
| title_fullStr | Utility of MPT64 antigen detection for rapid confirmation of mycobacterium tuberculosis complex |
| title_full_unstemmed | Utility of MPT64 antigen detection for rapid confirmation of mycobacterium tuberculosis complex |
| title_short | Utility of MPT64 antigen detection for rapid confirmation of mycobacterium tuberculosis complex |
| title_sort | utility of mpt64 antigen detection for rapid confirmation of mycobacterium tuberculosis complex |
| topic | Biochemical identification MPT64 antigen M. tuberculosis complex |
| url | http://www.jgid.org/article.asp?issn=0974-777X;year=2015;volume=7;issue=2;spage=66;epage=69;aulast=Arora |
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