A Review on the Significance of Elevated 1-hour Post-load Plasma Glucose during the Oral Glucose Tolerance Test

Elevated 1-hour post-load plasma glucose (1 hPG) concentration during the oral glucose tolerance test (OGTT) may be associated with insulin resistance and pancreatic β-cell dysfunction, and higher risks of diabetes and cardiovascular disease. We reviewed the studies related to the signifi...

Full description

Bibliographic Details
Main Author: HUANG Yucheng, DONG Aimei, HUANG Youyuan, FEI Xiuwen
Format: Article
Language:zho
Published: Chinese General Practice Publishing House Co., Ltd 2022-12-01
Series:Zhongguo quanke yixue
Subjects:
Online Access:https://www.chinagp.net/fileup/1007-9572/PDF/zx20220311.pdf
_version_ 1827289573003100160
author HUANG Yucheng, DONG Aimei, HUANG Youyuan, FEI Xiuwen
author_facet HUANG Yucheng, DONG Aimei, HUANG Youyuan, FEI Xiuwen
author_sort HUANG Yucheng, DONG Aimei, HUANG Youyuan, FEI Xiuwen
collection DOAJ
description Elevated 1-hour post-load plasma glucose (1 hPG) concentration during the oral glucose tolerance test (OGTT) may be associated with insulin resistance and pancreatic β-cell dysfunction, and higher risks of diabetes and cardiovascular disease. We reviewed the studies related to the significance of 1 hPG during the OGTT, in which 1 hPG during the OGTT has been reported to be prevalent in 10% to 40% of people with normal glucose tolerance, and the prevalence is higher in those with impaired glucose tolerance or impaired fasting glucose. Attention should be paid to the cutoff point of 1 hPG during the OGTT for the diagnosis of diabetes and pre-diabetes in Chinese population, which may be beneficial to early diagnosis and intervention of diabetes and pr-diabetes.
first_indexed 2024-04-24T11:52:55Z
format Article
id doaj.art-0656488708414b2fbe098bccbb4c0836
institution Directory Open Access Journal
issn 1007-9572
language zho
last_indexed 2024-04-24T11:52:55Z
publishDate 2022-12-01
publisher Chinese General Practice Publishing House Co., Ltd
record_format Article
series Zhongguo quanke yixue
spelling doaj.art-0656488708414b2fbe098bccbb4c08362024-04-09T06:33:23ZzhoChinese General Practice Publishing House Co., LtdZhongguo quanke yixue1007-95722022-12-0125354468447210.12114/j.issn.1007-9572.2022.0311A Review on the Significance of Elevated 1-hour Post-load Plasma Glucose during the Oral Glucose Tolerance TestHUANG Yucheng, DONG Aimei, HUANG Youyuan, FEI Xiuwen01Department of General Practice, Peking University First Hospital, Beijing 100034, China;2School of General Practice, Peking University Health Science Center, Beijing 100034, China;3Department of Endocrinology, Peking University First Hospital, Beijing 100034, ChinaElevated 1-hour post-load plasma glucose (1 hPG) concentration during the oral glucose tolerance test (OGTT) may be associated with insulin resistance and pancreatic β-cell dysfunction, and higher risks of diabetes and cardiovascular disease. We reviewed the studies related to the significance of 1 hPG during the OGTT, in which 1 hPG during the OGTT has been reported to be prevalent in 10% to 40% of people with normal glucose tolerance, and the prevalence is higher in those with impaired glucose tolerance or impaired fasting glucose. Attention should be paid to the cutoff point of 1 hPG during the OGTT for the diagnosis of diabetes and pre-diabetes in Chinese population, which may be beneficial to early diagnosis and intervention of diabetes and pr-diabetes.https://www.chinagp.net/fileup/1007-9572/PDF/zx20220311.pdfdiabetes mellitus, type 2|glucose tolerance test|glucose intolerance|1-hour post-load plasma glucose|prediabetic state
spellingShingle HUANG Yucheng, DONG Aimei, HUANG Youyuan, FEI Xiuwen
A Review on the Significance of Elevated 1-hour Post-load Plasma Glucose during the Oral Glucose Tolerance Test
Zhongguo quanke yixue
diabetes mellitus, type 2|glucose tolerance test|glucose intolerance|1-hour post-load plasma glucose|prediabetic state
title A Review on the Significance of Elevated 1-hour Post-load Plasma Glucose during the Oral Glucose Tolerance Test
title_full A Review on the Significance of Elevated 1-hour Post-load Plasma Glucose during the Oral Glucose Tolerance Test
title_fullStr A Review on the Significance of Elevated 1-hour Post-load Plasma Glucose during the Oral Glucose Tolerance Test
title_full_unstemmed A Review on the Significance of Elevated 1-hour Post-load Plasma Glucose during the Oral Glucose Tolerance Test
title_short A Review on the Significance of Elevated 1-hour Post-load Plasma Glucose during the Oral Glucose Tolerance Test
title_sort review on the significance of elevated 1 hour post load plasma glucose during the oral glucose tolerance test
topic diabetes mellitus, type 2|glucose tolerance test|glucose intolerance|1-hour post-load plasma glucose|prediabetic state
url https://www.chinagp.net/fileup/1007-9572/PDF/zx20220311.pdf
work_keys_str_mv AT huangyuchengdongaimeihuangyouyuanfeixiuwen areviewonthesignificanceofelevated1hourpostloadplasmaglucoseduringtheoralglucosetolerancetest
AT huangyuchengdongaimeihuangyouyuanfeixiuwen reviewonthesignificanceofelevated1hourpostloadplasmaglucoseduringtheoralglucosetolerancetest