A Review on the Significance of Elevated 1-hour Post-load Plasma Glucose during the Oral Glucose Tolerance Test
Elevated 1-hour post-load plasma glucose (1 hPG) concentration during the oral glucose tolerance test (OGTT) may be associated with insulin resistance and pancreatic β-cell dysfunction, and higher risks of diabetes and cardiovascular disease. We reviewed the studies related to the signifi...
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Format: | Article |
Language: | zho |
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Chinese General Practice Publishing House Co., Ltd
2022-12-01
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Series: | Zhongguo quanke yixue |
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Online Access: | https://www.chinagp.net/fileup/1007-9572/PDF/zx20220311.pdf |
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author | HUANG Yucheng, DONG Aimei, HUANG Youyuan, FEI Xiuwen |
author_facet | HUANG Yucheng, DONG Aimei, HUANG Youyuan, FEI Xiuwen |
author_sort | HUANG Yucheng, DONG Aimei, HUANG Youyuan, FEI Xiuwen |
collection | DOAJ |
description | Elevated 1-hour post-load plasma glucose (1 hPG) concentration during the oral glucose tolerance test (OGTT) may be associated with insulin resistance and pancreatic β-cell dysfunction, and higher risks of diabetes and cardiovascular disease. We reviewed the studies related to the significance of 1 hPG during the OGTT, in which 1 hPG during the OGTT has been reported to be prevalent in 10% to 40% of people with normal glucose tolerance, and the prevalence is higher in those with impaired glucose tolerance or impaired fasting glucose. Attention should be paid to the cutoff point of 1 hPG during the OGTT for the diagnosis of diabetes and pre-diabetes in Chinese population, which may be beneficial to early diagnosis and intervention of diabetes and pr-diabetes. |
first_indexed | 2024-04-24T11:52:55Z |
format | Article |
id | doaj.art-0656488708414b2fbe098bccbb4c0836 |
institution | Directory Open Access Journal |
issn | 1007-9572 |
language | zho |
last_indexed | 2024-04-24T11:52:55Z |
publishDate | 2022-12-01 |
publisher | Chinese General Practice Publishing House Co., Ltd |
record_format | Article |
series | Zhongguo quanke yixue |
spelling | doaj.art-0656488708414b2fbe098bccbb4c08362024-04-09T06:33:23ZzhoChinese General Practice Publishing House Co., LtdZhongguo quanke yixue1007-95722022-12-0125354468447210.12114/j.issn.1007-9572.2022.0311A Review on the Significance of Elevated 1-hour Post-load Plasma Glucose during the Oral Glucose Tolerance TestHUANG Yucheng, DONG Aimei, HUANG Youyuan, FEI Xiuwen01Department of General Practice, Peking University First Hospital, Beijing 100034, China;2School of General Practice, Peking University Health Science Center, Beijing 100034, China;3Department of Endocrinology, Peking University First Hospital, Beijing 100034, ChinaElevated 1-hour post-load plasma glucose (1 hPG) concentration during the oral glucose tolerance test (OGTT) may be associated with insulin resistance and pancreatic β-cell dysfunction, and higher risks of diabetes and cardiovascular disease. We reviewed the studies related to the significance of 1 hPG during the OGTT, in which 1 hPG during the OGTT has been reported to be prevalent in 10% to 40% of people with normal glucose tolerance, and the prevalence is higher in those with impaired glucose tolerance or impaired fasting glucose. Attention should be paid to the cutoff point of 1 hPG during the OGTT for the diagnosis of diabetes and pre-diabetes in Chinese population, which may be beneficial to early diagnosis and intervention of diabetes and pr-diabetes.https://www.chinagp.net/fileup/1007-9572/PDF/zx20220311.pdfdiabetes mellitus, type 2|glucose tolerance test|glucose intolerance|1-hour post-load plasma glucose|prediabetic state |
spellingShingle | HUANG Yucheng, DONG Aimei, HUANG Youyuan, FEI Xiuwen A Review on the Significance of Elevated 1-hour Post-load Plasma Glucose during the Oral Glucose Tolerance Test Zhongguo quanke yixue diabetes mellitus, type 2|glucose tolerance test|glucose intolerance|1-hour post-load plasma glucose|prediabetic state |
title | A Review on the Significance of Elevated 1-hour Post-load Plasma Glucose during the Oral Glucose Tolerance Test |
title_full | A Review on the Significance of Elevated 1-hour Post-load Plasma Glucose during the Oral Glucose Tolerance Test |
title_fullStr | A Review on the Significance of Elevated 1-hour Post-load Plasma Glucose during the Oral Glucose Tolerance Test |
title_full_unstemmed | A Review on the Significance of Elevated 1-hour Post-load Plasma Glucose during the Oral Glucose Tolerance Test |
title_short | A Review on the Significance of Elevated 1-hour Post-load Plasma Glucose during the Oral Glucose Tolerance Test |
title_sort | review on the significance of elevated 1 hour post load plasma glucose during the oral glucose tolerance test |
topic | diabetes mellitus, type 2|glucose tolerance test|glucose intolerance|1-hour post-load plasma glucose|prediabetic state |
url | https://www.chinagp.net/fileup/1007-9572/PDF/zx20220311.pdf |
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