Antitumor Effects of Intra-Arterial Delivery of Albumin-Doxorubicin Nanoparticle Conjugated Microbubbles Combined with Ultrasound-Targeted Microbubble Activation on VX2 Rabbit Liver Tumors

Antitumor Effects of Intra-Arterial Delivery of Albumin-Doxorubicin Nanoparticle Conjugated Microbubbles Combined with Ultrasound-Targeted Microbubble Activation on VX2 Rabbit Liver Tumors

Image-guided intra-arterial therapies play a key role in the management of hepatic malignancies. However, limited clinical outcomes suggest the need for new multifunctional drug delivery systems to enhance local drug concentration while reducing systemic adverse reactions. Therefore, we developed th...

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Bibliographic Details
Main Authors: Jae Hwan Lee, Hyungwon Moon, Hyounkoo Han, In Joon Lee, Doyeon Kim, Hak Jong Lee, Shin-Woo Ha, Hyuncheol Kim, Jin Wook Chung
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:Cancers
Subjects:
albumin nanoparticles
microbubble
ultrasound
theranostics
hepatocellular carcinoma
VX2 tumor
intra-arterial chemotherapy
Online Access:https://www.mdpi.com/2072-6694/11/4/581

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https://www.mdpi.com/2072-6694/11/4/581

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