Mutators and Long-Term Molecular Evolution of Pathogenic Escherichia coli O157:H7
It has been proposed that an increased mutation rate (indicated by the frequency of hypermutable isolates) has facilitated the emergence of Escherichia coli O157:H7. Analysis of the divergence of 12 genes shows no evidence that the pathogen has undergone an unusually high rate of mutation and molecu...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Centers for Disease Control and Prevention
1998-12-01
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| Series: | Emerging Infectious Diseases |
| Subjects: | |
| Online Access: | https://wwwnc.cdc.gov/eid/article/4/4/98-0411_article |
| _version_ | 1818186829088686080 |
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| author | Thomas S. Whittam Sean D. Reid Robert K. Selander |
| author_facet | Thomas S. Whittam Sean D. Reid Robert K. Selander |
| author_sort | Thomas S. Whittam |
| collection | DOAJ |
| description | It has been proposed that an increased mutation rate (indicated by the frequency of hypermutable isolates) has facilitated the emergence of Escherichia coli O157:H7. Analysis of the divergence of 12 genes shows no evidence that the pathogen has undergone an unusually high rate of mutation and molecular evolution. |
| first_indexed | 2024-12-11T23:01:21Z |
| format | Article |
| id | doaj.art-065fe67b60e34f44a17d7364235dcdc5 |
| institution | Directory Open Access Journal |
| issn | 1080-6040 1080-6059 |
| language | English |
| last_indexed | 2024-12-11T23:01:21Z |
| publishDate | 1998-12-01 |
| publisher | Centers for Disease Control and Prevention |
| record_format | Article |
| series | Emerging Infectious Diseases |
| spelling | doaj.art-065fe67b60e34f44a17d7364235dcdc52022-12-22T00:47:03ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60591998-12-014461561710.3201/eid0404.980411Mutators and Long-Term Molecular Evolution of Pathogenic Escherichia coli O157:H7Thomas S. WhittamSean D. ReidRobert K. SelanderIt has been proposed that an increased mutation rate (indicated by the frequency of hypermutable isolates) has facilitated the emergence of Escherichia coli O157:H7. Analysis of the divergence of 12 genes shows no evidence that the pathogen has undergone an unusually high rate of mutation and molecular evolution.https://wwwnc.cdc.gov/eid/article/4/4/98-0411_articleUnited States |
| spellingShingle | Thomas S. Whittam Sean D. Reid Robert K. Selander Mutators and Long-Term Molecular Evolution of Pathogenic Escherichia coli O157:H7 Emerging Infectious Diseases United States |
| title | Mutators and Long-Term Molecular Evolution of Pathogenic Escherichia coli O157:H7 |
| title_full | Mutators and Long-Term Molecular Evolution of Pathogenic Escherichia coli O157:H7 |
| title_fullStr | Mutators and Long-Term Molecular Evolution of Pathogenic Escherichia coli O157:H7 |
| title_full_unstemmed | Mutators and Long-Term Molecular Evolution of Pathogenic Escherichia coli O157:H7 |
| title_short | Mutators and Long-Term Molecular Evolution of Pathogenic Escherichia coli O157:H7 |
| title_sort | mutators and long term molecular evolution of pathogenic escherichia coli o157 h7 |
| topic | United States |
| url | https://wwwnc.cdc.gov/eid/article/4/4/98-0411_article |
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