Comparison of mammography and ultrasound findings in the follow-up of patients with breast cancer treated with segmental mastectomy followed by intraoperative electron radiotherapy versus external whole breast radiotherapy
PURPOSEThis study aims to describe imaging findings in patients treated with intraoperative electron radiotherapy and compare them with those detected in patients treated with external whole breast radiotherapy (WBRT).METHODSThe study population consisted of 25 patients who received intraoperative r...
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| Format: | Article |
| Language: | English |
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Galenos Publishing House
2023-11-01
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| Series: | Diagnostic and Interventional Radiology |
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http://www.dirjournal.org/archives/archive-detail/article-preview/comparison-of-mammography-and-ultrasound-findings-/58947
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| _version_ | 1827767271029735424 |
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| author | Burçin Tutar Gül Esen İçten Ayşe Altınok Seda Eröz Nuran Beşe Cihan Uras |
| author_facet | Burçin Tutar Gül Esen İçten Ayşe Altınok Seda Eröz Nuran Beşe Cihan Uras |
| author_sort | Burçin Tutar |
| collection | DOAJ |
| description | PURPOSEThis study aims to describe imaging findings in patients treated with intraoperative electron radiotherapy and compare them with those detected in patients treated with external whole breast radiotherapy (WBRT).METHODSThe study population consisted of 25 patients who received intraoperative radiotherapy [IORT (21 Gy)] as single-dose radiotherapy and a control group of 25 patients who received WBRT at the same institution. Mammography and ultrasound (US) findings were divided into three groups: minor, intermediate, and advanced. On mammography, mass lesions were considered advanced, and asymmetries or architectural distortions were considered intermediate. Oil cysts, linear scars, and the increase in parenchymal density were considered minor findings. On US, irregular non-mass lesions were considered advanced, and circumscribed hypoechoic lesions or planar irregular scars with shadowing were considered intermediate. Oil cysts, fluid collections, or linear scars were considered minor findings.RESULTSOn mammography, skin thickening (P = 0.001), edema (P < 0.001), increased parenchymal density (P < 0.001), dystrophic calcifications (P = 0.045), and scar/distortion (P = 0.005) were significantly more common in the WBRT group. On US, irregular non-mass lesions, which made interpretation considerably difficult, were significantly more common in the IORT group (P = 0.004). Dominant US findings were fluid collections and postoperative linear or planar scars in the WBRT group. Minor findings were more common in low-density breasts, and major findings (intermediate and advanced) were more common in high-density breasts on both mammographies (P = 0.011) and US (P = 0.027) in the IORT group.CONCLUSIONIll-defined non-mass lesions detected on US in the IORT group have not been defined previously. Radiologists should be aware of these lesions because they can be confusing, especially in early follow-up studies. This study has found that minor findings are seen more frequently in low-density breasts, while major findings are more common in high-density breasts in the IORT group. This has not been reported before, and further studies with more cases are needed to verify these results. |
| first_indexed | 2024-03-11T11:56:25Z |
| format | Article |
| id | doaj.art-0662842af8874719bfcdde4181f68a67 |
| institution | Directory Open Access Journal |
| issn | 1305-3825 1305-3612 |
| language | English |
| last_indexed | 2024-03-11T11:56:25Z |
| publishDate | 2023-11-01 |
| publisher | Galenos Publishing House |
| record_format | Article |
| series | Diagnostic and Interventional Radiology |
| spelling | doaj.art-0662842af8874719bfcdde4181f68a672023-11-08T12:27:32ZengGalenos Publishing HouseDiagnostic and Interventional Radiology1305-38251305-36122023-11-0129676177010.4274/dir.2023.21121813049054Comparison of mammography and ultrasound findings in the follow-up of patients with breast cancer treated with segmental mastectomy followed by intraoperative electron radiotherapy versus external whole breast radiotherapyBurçin Tutar0Gül Esen İçten1Ayşe Altınok2Seda Eröz3Nuran Beşe4Cihan Uras5 Clinic of Radiology, Acıbadem Maslak Hospital, İstanbul, Turkey Department of Radiology, Acıbadem University, Senology Research Institute, İstanbul, Turkey Clinic of Radiation Oncology, Bahçelievler Medical Park Hospital, İstanbul, Turkey Clinic of Radiation Oncology, Acıbadem Maslak Hospital, İstanbul, Turkey Department of Radiation Oncology, Acıbadem University, Senology Research Institute, İstanbul, Turkey Department of Breast Surgery, Acıbadem Mehmet Ali Aydınlar University, Research Institute of Senology, İstanbul, Turkey PURPOSEThis study aims to describe imaging findings in patients treated with intraoperative electron radiotherapy and compare them with those detected in patients treated with external whole breast radiotherapy (WBRT).METHODSThe study population consisted of 25 patients who received intraoperative radiotherapy [IORT (21 Gy)] as single-dose radiotherapy and a control group of 25 patients who received WBRT at the same institution. Mammography and ultrasound (US) findings were divided into three groups: minor, intermediate, and advanced. On mammography, mass lesions were considered advanced, and asymmetries or architectural distortions were considered intermediate. Oil cysts, linear scars, and the increase in parenchymal density were considered minor findings. On US, irregular non-mass lesions were considered advanced, and circumscribed hypoechoic lesions or planar irregular scars with shadowing were considered intermediate. Oil cysts, fluid collections, or linear scars were considered minor findings.RESULTSOn mammography, skin thickening (P = 0.001), edema (P < 0.001), increased parenchymal density (P < 0.001), dystrophic calcifications (P = 0.045), and scar/distortion (P = 0.005) were significantly more common in the WBRT group. On US, irregular non-mass lesions, which made interpretation considerably difficult, were significantly more common in the IORT group (P = 0.004). Dominant US findings were fluid collections and postoperative linear or planar scars in the WBRT group. Minor findings were more common in low-density breasts, and major findings (intermediate and advanced) were more common in high-density breasts on both mammographies (P = 0.011) and US (P = 0.027) in the IORT group.CONCLUSIONIll-defined non-mass lesions detected on US in the IORT group have not been defined previously. Radiologists should be aware of these lesions because they can be confusing, especially in early follow-up studies. This study has found that minor findings are seen more frequently in low-density breasts, while major findings are more common in high-density breasts in the IORT group. This has not been reported before, and further studies with more cases are needed to verify these results. http://www.dirjournal.org/archives/archive-detail/article-preview/comparison-of-mammography-and-ultrasound-findings-/58947 breastintraoperative radiotherapywhole breast radiotherapymammographyultrasonography |
| spellingShingle | Burçin Tutar Gül Esen İçten Ayşe Altınok Seda Eröz Nuran Beşe Cihan Uras Comparison of mammography and ultrasound findings in the follow-up of patients with breast cancer treated with segmental mastectomy followed by intraoperative electron radiotherapy versus external whole breast radiotherapy Diagnostic and Interventional Radiology breast intraoperative radiotherapy whole breast radiotherapy mammography ultrasonography |
| title | Comparison of mammography and ultrasound findings in the follow-up of patients with breast cancer treated with segmental mastectomy followed by intraoperative electron radiotherapy versus external whole breast radiotherapy |
| title_full | Comparison of mammography and ultrasound findings in the follow-up of patients with breast cancer treated with segmental mastectomy followed by intraoperative electron radiotherapy versus external whole breast radiotherapy |
| title_fullStr | Comparison of mammography and ultrasound findings in the follow-up of patients with breast cancer treated with segmental mastectomy followed by intraoperative electron radiotherapy versus external whole breast radiotherapy |
| title_full_unstemmed | Comparison of mammography and ultrasound findings in the follow-up of patients with breast cancer treated with segmental mastectomy followed by intraoperative electron radiotherapy versus external whole breast radiotherapy |
| title_short | Comparison of mammography and ultrasound findings in the follow-up of patients with breast cancer treated with segmental mastectomy followed by intraoperative electron radiotherapy versus external whole breast radiotherapy |
| title_sort | comparison of mammography and ultrasound findings in the follow up of patients with breast cancer treated with segmental mastectomy followed by intraoperative electron radiotherapy versus external whole breast radiotherapy |
| topic | breast intraoperative radiotherapy whole breast radiotherapy mammography ultrasonography |
| url |
http://www.dirjournal.org/archives/archive-detail/article-preview/comparison-of-mammography-and-ultrasound-findings-/58947
|
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